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==Microscopic== | ==Microscopic== | ||
Features:<ref name=emed_paget>URL: [http://emedicine.medscape.com/article/311688-overview http://emedicine.medscape.com/article/311688-overview]. Accessed on: 25 December 2010.</ref> | Features:<ref name=emed_paget>URL: [http://emedicine.medscape.com/article/311688-overview http://emedicine.medscape.com/article/311688-overview]. Accessed on: 25 December 2010.</ref> | ||
*Early Paget disease is cellular and fibro-osseous (bone and fibrous components) | |||
*Mature Paget disease is sclerotic with thickened bone trabeculae. | |||
*Bone matrix has jigsaw-puzzle like pattern. | *Bone matrix has jigsaw-puzzle like pattern. | ||
**Jigsaw-puzzle pieces each ~ 100-500 micrometres in size (largest dimension). | **Jigsaw-puzzle pieces each ~ 100-500 micrometres in size (largest dimension). |
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