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Difference between revisions of "Adenocarcinoma of the rete testis"
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Adenocarcinoma of the rete testis (view source)
Revision as of 07:05, 16 December 2014
, 07:05, 16 December 2014no edit summary
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| Caption = Adenocarcinoma of the rete testis. [[H&E stain]]. | | Caption = Adenocarcinoma of the rete testis. [[H&E stain]]. | ||
| Synonyms = | | Synonyms = | ||
| Micro = | | Micro = atypical columnar or cuboidal cells, often with cigar-shaped nuclei; classically tubular or papillary architecture; transistion to normal appearing rete testis | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[adenomatous hyperplasia of the rete testis]], [[Sertoli cell tumour]], [[malignant mesothelioma]], metastasis | | LMDDx = [[adenomatous hyperplasia of the rete testis]], [[Sertoli cell tumour]], [[malignant mesothelioma]], metastasis | ||
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| Symptoms = | | Symptoms = | ||
| Prevalence = extremely rare | | Prevalence = extremely rare | ||
| Bloodwork = | | Bloodwork = markers for GCT typically normal | ||
| Rads = | | Rads = | ||
| Endoscopy = | | Endoscopy = | ||
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*Possible association of diethylstilbestrol.<ref name=pmid3799821>{{Cite journal | last1 = Newbold | first1 = RR. | last2 = Bullock | first2 = BC. | last3 = McLachlan | first3 = JA. | title = Adenocarcinoma of the rete testis. Diethylstilbestrol-induced lesions of the mouse rete testis. | journal = Am J Pathol | volume = 125 | issue = 3 | pages = 625-8 | month = Dec | year = 1986 | doi = | PMID = 3799821 | PMC = 1888460 | URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888460/?page=1}}</ref> | *Possible association of diethylstilbestrol.<ref name=pmid3799821>{{Cite journal | last1 = Newbold | first1 = RR. | last2 = Bullock | first2 = BC. | last3 = McLachlan | first3 = JA. | title = Adenocarcinoma of the rete testis. Diethylstilbestrol-induced lesions of the mouse rete testis. | journal = Am J Pathol | volume = 125 | issue = 3 | pages = 625-8 | month = Dec | year = 1986 | doi = | PMID = 3799821 | PMC = 1888460 | URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888460/?page=1}}</ref> | ||
*Prognosis poor<ref name=pmid17853037>{{Cite journal | last1 = Sogni | first1 = F. | last2 = Monga | first2 = G. | last3 = Terrone | first3 = C. | last4 = Gontero | first4 = P. | title = Primary adenocarcinoma of the rete testis: diagnostic problems and therapeutic dilemmas. | journal = Scand J Urol Nephrol | volume = 42 | issue = 1 | pages = 83-5 | month = | year = 2008 | doi = 10.1080/00365590701517608 | PMID = 17853037 }}</ref> - 3-year and 5-year disease-free survival approximately 50% and 15% respectively.<ref name=pmid7571213>{{Cite journal | last1 = Sánchez-Chapado | first1 = M. | last2 = Angulo | first2 = JC. | last3 = Haas | first3 = GP. | title = Adenocarcinoma of the rete testis. | journal = Urology | volume = 46 | issue = 4 | pages = 468-75 | month = Oct | year = 1995 | doi = 10.1016/S0090-4295(99)80257-X | PMID = 7571213 }}</ref> | *Prognosis poor<ref name=pmid17853037>{{Cite journal | last1 = Sogni | first1 = F. | last2 = Monga | first2 = G. | last3 = Terrone | first3 = C. | last4 = Gontero | first4 = P. | title = Primary adenocarcinoma of the rete testis: diagnostic problems and therapeutic dilemmas. | journal = Scand J Urol Nephrol | volume = 42 | issue = 1 | pages = 83-5 | month = | year = 2008 | doi = 10.1080/00365590701517608 | PMID = 17853037 }}</ref> - 3-year and 5-year disease-free survival approximately 50% and 15% respectively.<ref name=pmid7571213>{{Cite journal | last1 = Sánchez-Chapado | first1 = M. | last2 = Angulo | first2 = JC. | last3 = Haas | first3 = GP. | title = Adenocarcinoma of the rete testis. | journal = Urology | volume = 46 | issue = 4 | pages = 468-75 | month = Oct | year = 1995 | doi = 10.1016/S0090-4295(99)80257-X | PMID = 7571213 }}</ref> | ||
Clinical: | |||
*[[Germ cell tumour]] serum markers (LDH, AFP, beta-hCG) typically normal. | |||
==Gross== | ==Gross== | ||
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*Adenocarcinoma: | *Adenocarcinoma: | ||
**Atypical columnar or cuboidal cells, often with cigar-shaped nuclei. | **Atypical columnar or cuboidal cells, often with cigar-shaped nuclei. | ||
** | **Classically tubular or papillary architecture.<ref name=pmid3799821/> | ||
*Transistion to normal appearing rete testis.<ref name=pmid6465420/> | *Transistion to normal appearing rete testis.<ref name=pmid6465420/> | ||