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Difference between revisions of "Adenocarcinoma of the rete testis"
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Adenocarcinoma of the rete testis (view source)
Revision as of 06:52, 16 December 2014
, 06:52, 16 December 2014no edit summary
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{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
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==General== | ==General== | ||
*Extremely rare - a few dozen cases in the world literature.<ref name=pmid3799821>{{Cite journal | last1 = Newbold | first1 = RR. | last2 = Bullock | first2 = BC. | last3 = McLachlan | first3 = JA. | title = Adenocarcinoma of the rete testis. Diethylstilbestrol-induced lesions of the mouse rete testis. | journal = Am J Pathol | volume = 125 | issue = 3 | pages = 625-8 | month = Dec | year = 1986 | doi = | PMID = 3799821 | PMC = 1888460 | URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888460/?page=1}}</ref | *Extremely rare<ref name=pmid6465420>{{Cite journal | last1 = Nochomovitz | first1 = LE. | last2 = Orenstein | first2 = JM. | title = Adenocarcinoma of the rete testis. Case report, ultrastructural observations, and clinicopathologic correlates. | journal = Am J Surg Pathol | volume = 8 | issue = 8 | pages = 625-34 | month = Aug | year = 1984 | doi = | PMID = 6465420 }}</ref> - a few dozen cases in the world literature. | ||
*Typically older men (>60 years old), but reported in younger men with undescended testis.<ref name=pmid6465420/> | |||
*Possible association of diethylstilbestrol.<ref name=pmid3799821>{{Cite journal | last1 = Newbold | first1 = RR. | last2 = Bullock | first2 = BC. | last3 = McLachlan | first3 = JA. | title = Adenocarcinoma of the rete testis. Diethylstilbestrol-induced lesions of the mouse rete testis. | journal = Am J Pathol | volume = 125 | issue = 3 | pages = 625-8 | month = Dec | year = 1986 | doi = | PMID = 3799821 | PMC = 1888460 | URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888460/?page=1}}</ref> | |||
*Prognosis poor<ref name=pmid17853037>{{Cite journal | last1 = Sogni | first1 = F. | last2 = Monga | first2 = G. | last3 = Terrone | first3 = C. | last4 = Gontero | first4 = P. | title = Primary adenocarcinoma of the rete testis: diagnostic problems and therapeutic dilemmas. | journal = Scand J Urol Nephrol | volume = 42 | issue = 1 | pages = 83-5 | month = | year = 2008 | doi = 10.1080/00365590701517608 | PMID = 17853037 }}</ref> - 3-year and 5-year disease-free survival approximately 50% and 15% respectively.<ref name=pmid7571213>{{Cite journal | last1 = Sánchez-Chapado | first1 = M. | last2 = Angulo | first2 = JC. | last3 = Haas | first3 = GP. | title = Adenocarcinoma of the rete testis. | journal = Urology | volume = 46 | issue = 4 | pages = 468-75 | month = Oct | year = 1995 | doi = 10.1016/S0090-4295(99)80257-X | PMID = 7571213 }}</ref> | *Prognosis poor<ref name=pmid17853037>{{Cite journal | last1 = Sogni | first1 = F. | last2 = Monga | first2 = G. | last3 = Terrone | first3 = C. | last4 = Gontero | first4 = P. | title = Primary adenocarcinoma of the rete testis: diagnostic problems and therapeutic dilemmas. | journal = Scand J Urol Nephrol | volume = 42 | issue = 1 | pages = 83-5 | month = | year = 2008 | doi = 10.1080/00365590701517608 | PMID = 17853037 }}</ref> - 3-year and 5-year disease-free survival approximately 50% and 15% respectively.<ref name=pmid7571213>{{Cite journal | last1 = Sánchez-Chapado | first1 = M. | last2 = Angulo | first2 = JC. | last3 = Haas | first3 = GP. | title = Adenocarcinoma of the rete testis. | journal = Urology | volume = 46 | issue = 4 | pages = 468-75 | month = Oct | year = 1995 | doi = 10.1016/S0090-4295(99)80257-X | PMID = 7571213 }}</ref> | ||
==Gross== | |||
*Lesion of the testicular hilum.<ref name=pmid6465420/> | |||
==Microscopic== | ==Microscopic== | ||
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*Adenocarcinoma: | *Adenocarcinoma: | ||
**Tubular or papillary architecture.<ref name=pmid3799821/> | **Tubular or papillary architecture.<ref name=pmid3799821/> | ||
**Columnar cells with cigar-shaped nuclei. | **Columnar or cuboidal cells, often with cigar-shaped nuclei. | ||
*Transistion to normal appearing rete testis.<ref name=pmid6465420/> | |||
DDx: | DDx: | ||
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*[[Metastatic]] carcinoma involving the testis - usually [[prostate carcinoma|prostate]], kidney, or colon.<ref name=pmid18769334>{{Cite journal | last1 = Ulbright | first1 = TM. | last2 = Young | first2 = RH. | title = Metastatic carcinoma to the testis: a clinicopathologic analysis of 26 nonincidental cases with emphasis on deceptive features. | journal = Am J Surg Pathol | volume = 32 | issue = 11 | pages = 1683-93 | month = Nov | year = 2008 | doi = 10.1097/PAS.0b013e3181788516 | PMID = 18769334 }}</ref> | *[[Metastatic]] carcinoma involving the testis - usually [[prostate carcinoma|prostate]], kidney, or colon.<ref name=pmid18769334>{{Cite journal | last1 = Ulbright | first1 = TM. | last2 = Young | first2 = RH. | title = Metastatic carcinoma to the testis: a clinicopathologic analysis of 26 nonincidental cases with emphasis on deceptive features. | journal = Am J Surg Pathol | volume = 32 | issue = 11 | pages = 1683-93 | month = Nov | year = 2008 | doi = 10.1097/PAS.0b013e3181788516 | PMID = 18769334 }}</ref> | ||
*[[Sertoli cell tumour]]. | *[[Sertoli cell tumour]]. | ||
*[[Malignant mesothelioma]].<ref name=pmid6465420/> | |||
===Images=== | ===Images=== | ||