Difference between revisions of "Embryonal carcinoma"

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753 bytes added ,  15:48, 26 November 2014
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#Indistinct cell borders
#Indistinct cell borders
#Mitoses - common.
#Mitoses - common.
#Variable architecture:
#Variable architecture:<ref name=pmid24503753>{{Cite journal  | last1 = Kao | first1 = CS. | last2 = Ulbright | first2 = TM. | last3 = Young | first3 = RH. | last4 = Idrees | first4 = MT. | title = Testicular embryonal carcinoma: a morphologic study of 180 cases highlighting unusual and unemphasized aspects. | journal = Am J Surg Pathol | volume = 38 | issue = 5 | pages = 689-97 | month = May | year = 2014 | doi = 10.1097/PAS.0000000000000171 | PMID = 24503753 }}</ref>
#*Tubulopapillary.
#*Solid (predominant in ~55% of cases).
#*Glandular.
#*Glandular (predominant in ~17% of cases).
#*Solid.  
#*Papillary (predominant in ~11% of cases).
#*Nested.
#*Micropapillary.
#*Anastomosing glandular.
#*Sieve-like glandular.
#*Pseudopapillary.
#*Blastocyst-like.
#*Embryoid bodies - ball of cells in surrounded by empty space on three sides.
#*Embryoid bodies - ball of cells in surrounded by empty space on three sides.


Notes:
Notes:
*Cytoplasmic staining variable (eosinophilic to basophilic).
*Cytoplasmic staining variable (eosinophilic to basophilic).
*[[Syncytiotrophoblasts]] commonly seen (~40-50% of cases<ref name=pmid24503753/>).


DDx:
DDx:
*[[Mixed germ cell tumour]].
*[[Mixed germ cell tumour]].
*[[Yolk sac tumour]].
*[[Yolk sac tumour]].
*[[Seminoma]].


===Images===
===Images===
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