Difference between revisions of "Salivary glands"

Salivary glands (view source)

827 bytes added , 04:52, 11 January 2011

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 ==Carcinoma ex pleomorphic adenoma==
-*Malignant transformation of ''pleomorphic adenoma''.
+*Abbreviated ''Ca ex PA''.
+===General===
+Definition:
+*Malignant transformation of a ''pleomorphic adenoma''.
+Diagnosis (either 1 or 2):
+#History of a pleomorphic adenoma at the same site.
+#Features of a pleomorphic adenoma and a carcinoma.
+Epidemiology:
 *Rare.
-*May be subtle.
 ===Microscopy===
 Features:
-*Nests of cells, may from glands, single cells. (???)
+*Cells with cytologic features of malignancy.
+*Architecture (any of the following):
+**Glands.
+**Nests.
+**Single cells (may be subtle).
+Architectural patterns:
+*Ductal carcinoma NOS (arising from ductal cells) - most common pattern for Ca ex PA.
+*Myoepithelial cacinoma NOS (arising from myoepithelial cells).
+*"Named carcinoma":
+**Salivary duct carcinoma - second most common pattern for Ca ex PA.
+**Mucoepidermoid carcinoma.
+**Adenoid cystic carcinoma.
 Note:
-*Adenocarcinoma-like.
+*Often adenocarcinoma-like.
+*Myoepithelial cells may be clear cells. (???)
+====Subclassification====
+#Non-invasive [[AKA]] ''intracapsular'' [[AKA]] ''in situ''.
+#Minimally invasive <1.5 mm beyond the capsule.
+#Widely invasive >=1.5 mm beyond the capsule.
 ==Sebaceous carcinoma==