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Difference between revisions of "Kidney tumours"
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→ISUP grading
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===ISUP grading=== | ===ISUP grading=== | ||
Criteria:<ref name=pmid24025520/> | Criteria:<ref name=pmid24025520/> | ||
*Grade 1 - nucleoli | *Grade 1 - nucleoli absent/very small at 400x. § | ||
*Grade 2 - nucleoli seen with | *Grade 2 - nucleoli seen with 400x, but not at 100x. §§ | ||
*Grade 3 - nucleoli seen with 10x objective. | *Grade 3 - nucleoli seen at 100x, i.e. with the 10x objective. | ||
*Grade 4 - extreme nuclear pleomorphism (esp. nuclear enlargement) ''or'' [[renal cell carcinoma with sarcomatoid differentiation|sarcomatoid differentiation]] ([[spindle cell]]s<ref name=pmid15763002/> or [[Renal cell carcinoma with rhabdoid morphology|rhabdoid cells]]). | *Grade 4 - extreme nuclear pleomorphism (esp. nuclear enlargement) ''or'' [[renal cell carcinoma with sarcomatoid differentiation|sarcomatoid differentiation]] ([[spindle cell]]s<ref name=pmid15763002/> or [[Renal cell carcinoma with rhabdoid morphology|rhabdoid cells]]). | ||
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*† Suffers from [[IPFitis]]. | *† Suffers from [[IPFitis]]. | ||
*‡ Suffers from [[HPFitis]]. | *‡ Suffers from [[HPFitis]]. | ||
*§ Some describe Grade 1 nuclei as ''lymphocyte-like''.{{fact}} | |||
*§§ Some suggest the following relationship between grading/nucleoli:{{fact}} | |||
**Grade 1 = nucleoli seen at 400x. | |||
**Grade 2 = nucleoli seen at 200x. | |||
**Grade 3 = nucleoli seen at 100x. | |||
==Clear cell renal cell carcinoma== | ==Clear cell renal cell carcinoma== | ||