Difference between revisions of "Kidney tumours"

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Kidney tumours (view source)

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→‎Juxtaglomerular cell tumour: split out
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=Rare stuffs=
=Rare stuffs=
==Juxtaglomerular cell tumour==
==Juxtaglomerular cell tumour==
*[[AKA]] juxtaglomerular tumour, reninoma.<ref name=pmid18192852/>
*[[AKA]] juxtaglomerular tumour, reninoma.<ref name=pmid18192852>{{Cite journal  | last1 = Wong | first1 = L. | last2 = Hsu | first2 = TH. | last3 = Perlroth | first3 = MG. | last4 = Hofmann | first4 = LV. | last5 = Haynes | first5 = CM. | last6 = Katznelson | first6 = L. | title = Reninoma: case report and literature review. | journal = J Hypertens | volume = 26 | issue = 2 | pages = 368-73 | month = Feb | year = 2008 | doi = 10.1097/HJH.0b013e3282f283f3 | PMID = 18192852 }}</ref>
===General===
{{Main|Juxtaglomerular cell tumour}}
*Rare.
*Etiology: increased renin.
 
Clinical:<ref name=pmid18192852>{{Cite journal  | last1 = Wong | first1 = L. | last2 = Hsu | first2 = TH. | last3 = Perlroth | first3 = MG. | last4 = Hofmann | first4 = LV. | last5 = Haynes | first5 = CM. | last6 = Katznelson | first6 = L. | title = Reninoma: case report and literature review. | journal = J Hypertens | volume = 26 | issue = 2 | pages = 368-73 | month = Feb | year = 2008 | doi = 10.1097/HJH.0b013e3282f283f3 | PMID = 18192852 }}</ref>
*[[Hypertension]].
*Increased aldosterone.
**Causes hypokalemia.
*Increased plasma renin.
 
===Microscopic===
Features:<ref name=pmid21191395/>
*Polygonal cells.
*Abundant granular, eosinophilic cytoplasm.<ref name=pmid436071/>
*Perinuclear halo.
 
DDx:
*[[Chromophobe renal cell carcinoma]], eosinophilic variant.
 
Image:
*[http://www.nature.com/ki/journal/v79/n2/fig_tab/ki2010445f1.html#figure-title Reninoma (nature.com)].<ref name=pmid21191395/>
 
===Stains===
Cytoplasmic granules.<ref name=pmid436071>{{Cite journal  | last1 = Hanna | first1 = W. | last2 = Tepperman | first2 = B. | last3 = Logan | first3 = AG. | last4 = Robinette | first4 = MA. | last5 = Colapinto | first5 = R. | last6 = Phillips | first6 = MJ. | title = Juxtaglomerular cell tumour (reninoma) with paroxysmal hypertension. | journal = Can Med Assoc J | volume = 120 | issue = 8 | pages = 957-9 | month = Apr | year = 1979 | doi =  | PMID = 436071 PMC = 1819229 | URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1819229/?tool=pubmed }}</ref>
*PAS +ve.
*PASD +ve.
 
===IHC===
Features:<ref name=pmid21191395>{{Cite journal  | last1 = Chao | first1 = CT. | last2 = Chang | first2 = FC. | last3 = Wu | first3 = VC. | last4 = Chen | first4 = JC. | title = Reninoma. | journal = Kidney Int | volume = 79 | issue = 2 | pages = 260 | month = Jan | year = 2011 | doi = 10.1038/ki.2010.445 | PMID = 21191395 }}</ref>
*Actin +ve.
*Cytokeratin -ve.
*HMB-45 -ve.
 
===EM===
Features:
*Vesicles - contain renin.<ref name=upmc29>URL: [http://path.upmc.edu/cases/case29/micro.html http://path.upmc.edu/cases/case29/micro.html]. Accessed on: 18 December 2011.</ref>


==Renomedullary interstitial cell tumour==
==Renomedullary interstitial cell tumour==
Michael
49,021

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