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*Large & multiple leiomyomas are associated with infertility. | *Large & multiple leiomyomas are associated with infertility. | ||
*May be part of ''[[hereditary leiomyomatosis and renal cell cancer]]'' (HLRCC). | *May be part of ''[[hereditary leiomyomatosis and renal cell cancer]]'' (HLRCC). | ||
**In one series, | **In one series, 68% with HLRCC were diagnosed at age <=30 years.<ref name=pmid16597677>{{Cite journal | last1 = Pithukpakorn | first1 = M. | last2 = Wei | first2 = MH. | last3 = Toure | first3 = O. | last4 = Steinbach | first4 = PJ. | last5 = Glenn | first5 = GM. | last6 = Zbar | first6 = B. | last7 = Linehan | first7 = WM. | last8 = Toro | first8 = JR. | title = Fumarate hydratase enzyme activity in lymphoblastoid cells and fibroblasts of individuals in families with hereditary leiomyomatosis and renal cell cancer. | journal = J Med Genet | volume = 43 | issue = 9 | pages = 755-62 | month = Sep | year = 2006 | doi = 10.1136/jmg.2006.041087 | PMID = 16597677 }} | ||
</ref> | </ref> | ||
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