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'''[[Heart]] transplant pathology''' is a niche in [[cardiac pathology]]. | '''[[Heart]] transplant pathology''' is a niche in [[cardiac pathology]]. | ||
It comes in different flavours: | |||
*Acute vascular rejection. | |||
*Cellular rejection. | |||
*Chronic rejection. | |||
==Biopsy site reaction== | |||
===General=== | |||
*Can be confused for rejection. | |||
===Microscopic=== | |||
Features: | |||
*Hemosiderin-laden macrophages. | |||
*+/-Fibrosis/myofibre loss-replacement. | |||
*+/-Scant inflammatory infiltration. | |||
Image: [http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675%2806%2970592-7&figureId=fig6 Biopsy site (pathconsultddx.com)]. | |||
==Acute rejection== | |||
===Microscopic=== | |||
Features:<ref>URL: [http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675%2806%2970592-7&figureId=fig4 http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675%2806%2970592-7&figureId=fig4]. Accessed on: 7 January 2011.</ref> | |||
*Edema. | |||
*Dilated small vessels. | |||
*Scant inflammatory infiltrate. | |||
Image: | |||
*[http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675%2806%2970592-7&figureId=fig4 Acute rejection (pathconsultddx.com)]. | |||
==Cellular rejection== | ==Cellular rejection== | ||
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==Chronic rejection== | |||
===Microscopic=== | |||
Features:<ref>URL: [http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675%2806%2970592-7&figureId=fig5 http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675%2806%2970592-7&figureId=fig5]. Accessed on: 7 January 2011.</ref> | |||
*Concentric intimal thickening. | |||
*Preservation of internal elastic lamina. | |||
Image: [http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675%2806%2970592-7&figureId=fig5 Chronic rejection (pathconsultddx.com)]. | |||
Notes: | |||
*Vague similar to atherosclerosis. | |||
==See also== | ==See also== | ||
*[[Heart]]. | *[[Heart]]. | ||
*[[Lung transplant pathology]]. | |||
==References== | ==References== |
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