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==General== | ==General== | ||
*Extremely rare. | *Extremely rare - less than 15 cases reported in the literature.<ref name=pmid24025519/> | ||
*Large age range (29-83 years old). | |||
==Gross== | |||
*Solid, brown and well circumscribed. | |||
==Microscopic== | ==Microscopic== | ||
Features: | Features:<ref name=pmid24025519/> | ||
*Thyroid follicule-like structures | *Thyroid follicule-like structures - both microfollicular and/or microfollicular. **Contain dense-appearing eosinophilic material. | ||
*Encapuslated. | |||
*Nuclei round and regular with prominent nucleoli ([[ISUP nucleolar grade]] 2 or 3). | |||
DDx: | |||
*Metastatic carcinoma. | |||
**[[Follicular thyroid carcinoma]]. | |||
**[[Papillary thyroid carcinoma follicular variant]]. | |||
==IHC== | |||
Features:<ref name=pmid24025519/> | |||
*TTF-1 -ve. | |||
*Thyroglobulin -ve. | |||
*CK7 +ve/-ve. | |||
*PAX8 +ve/-ve. | |||
==See also== | ==See also== |
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