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Difference between revisions of "Chondroblastoma"
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→Microscopic
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Features:<ref name=Ref_WMSP_642>{{Ref WMSP|642}}</ref> | Features:<ref name=Ref_WMSP_642>{{Ref WMSP|642}}</ref> | ||
*Abundant extracellular material - pink on [[H&E stain]] - looks vaguely like cartilage. | *Abundant extracellular material - pink on [[H&E stain]] - looks vaguely like cartilage. | ||
*Sometimes described as 'immature cartilage' (very narrow DDX for this type of cartilage) | |||
*Chondroblasts: | *Chondroblasts: | ||
**Nuclear morphology variable: ovoid, folded or grooved. | **Nuclear morphology variable: ovoid, folded or grooved. | ||
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*+/-[[Giant cells]]. | *+/-[[Giant cells]]. | ||
**May lead to confusion with ''[[giant cell tumour of bone]]''. | **May lead to confusion with ''[[giant cell tumour of bone]]''. | ||
**Not infrequently associated with an aneurysmal bone cyst.<ref>{{Cite journal | last1 = Sepah | first1 = YJ. | last2 = Umer | first2 = M. | last3 = Minhas | first3 = K. | last4 = Hafeez | first4 = K. | title = Chondroblastoma of the cuboid with an associated aneurysmal bone cyst: a case report. | journal = J Med Case Rep | volume = 1 | issue = | pages = 135 | month = | year = 2007 | doi = 10.1186/1752-1947-1-135 | PMID = 17999776 }}</ref> | |||
DDx: | DDx: | ||
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*[[Chondroma]]. | *[[Chondroma]]. | ||
*Well-differentiated [[chondrosarcoma]]. | *Well-differentiated [[chondrosarcoma]]. | ||
*Chondromyxoid fibroma - also has 'immature cartilage' | |||
*[[Aneurysmal bone cyst]] - dont forget that these may be secondary to another lesion. | |||
===Images=== | ===Images=== | ||
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Image:Chondroblastoma_-_intermed_mag.jpg | Chondroblastoma - intermed. mag. (WC) | Image:Chondroblastoma_-_intermed_mag.jpg | Chondroblastoma - intermed. mag. (WC) | ||
Image:Chondroblastoma_-_very_high_mag.jpg | Chondroblastoma - very high mag. (WC) | Image:Chondroblastoma_-_very_high_mag.jpg | Chondroblastoma - very high mag. (WC) | ||
Image:Bone Chondroblastoma Medium Power.jpg|Chicken wire calcification. (SKB) | |||
Image:Bone Chondroblastoma High Power.jpg|Chicken wire calcification. (SKB) | |||
Image:Bone Chondroblastoma With Aneurysmal Bone Cyst - Medium Power.jpg|Immature cartilage (left) abutting aneurysmal bone cyst (right) with giant cells. (SKB) | |||
Image:Bone Chondroblastoma - Medium Power.jpg|thumb|Immature cartilage]] | |||
Image:Bone Chondroblastoma and Aneurysmal Bone Cyst Low Power.jpg|Immature cartilage surrounded by aneurysmal bone cyst with giant cells. (SKB) | |||
Image:Bone Chondroblastoma and Aneurysmal Bone Cyst Low Power.jpg|Immature cartilage surrounded by aneurysmal bone cyst with giant cells. (SKB) | |||
</gallery> | </gallery> | ||
www: | www: | ||