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Difference between revisions of "Cystic medial degeneration"
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Cystic medial degeneration (view source)
Revision as of 05:54, 19 October 2014
, 05:54, 19 October 2014no edit summary
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Cystic_medial_degeneration_-_high_mag.jpg | |||
| Width = | |||
| Caption = Cystic medial degeneration. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = basophilic ground substance in the media (seen on Movat's [[stain]]), disruption of the elastic lamina (seen on elastic trichrome stain), +/-focal necrosis. | |||
| Subtypes = | |||
| LMDDx = aortic dissection without apparent underlying pathology | |||
| Stains = [[Movat's stain]] (basophilic ground substance present), elastin stain (fragmentation of elastin) | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[blood vessels|large arteries]] | |||
| Assdx = | |||
| Syndromes = [[Marfan's syndrome]] | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = chest pain, shortness of breath | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = dependent on severity and associated pathology | |||
| Other = | |||
| ClinDDx = [[myocardial infarction]], other causes of chest pain, others | |||
| Tx = surgical repair or conservative management - see [[aortic dissection]] | |||
}} | |||
'''Cystic medial degeneration''' (abbreviated '''CMD'''), also '''cystic medial necrosis''',<ref>URL: [http://emedicine.medscape.com/article/756835-overview http://emedicine.medscape.com/article/756835-overview]. Accessed on: 12 August 2010.</ref> is [[vascular disease|vascular pathology]] of the large [[blood vessel]]s. It is suggestive of an underlying [[connective tissue disorder]]. | '''Cystic medial degeneration''' (abbreviated '''CMD'''), also '''cystic medial necrosis''',<ref>URL: [http://emedicine.medscape.com/article/756835-overview http://emedicine.medscape.com/article/756835-overview]. Accessed on: 12 August 2010.</ref> is [[vascular disease|vascular pathology]] of the large [[blood vessel]]s. It is suggestive of an underlying [[connective tissue disorder]]. | ||