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Difference between revisions of "Peripheral nerve sheath tumours"
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Peripheral nerve sheath tumours (view source)
Revision as of 02:50, 7 January 2011
, 02:50, 7 January 2011→Neurofibroma: +IHC
(→Neurofibroma: +IHC) |
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Features:<ref name=pmid17893219/> | Features:<ref name=pmid17893219/> | ||
*Plexiform growth pattern - "bag of worms". | *Plexiform growth pattern - "bag of worms". | ||
DDx: | |||
*Schwannoma. | |||
*Dermatofibrosarcoma protuberans (DFSP) - S-100 -ve, CD34 +ve. | |||
*[[Ganglioneuroma]]. | |||
Image: | Image: | ||
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*[http://commons.wikimedia.org/wiki/File:Neurofibroma_(2).jpg Neurofibroma - high mag. (WC)]. | *[http://commons.wikimedia.org/wiki/File:Neurofibroma_(2).jpg Neurofibroma - high mag. (WC)]. | ||
*[http://commons.wikimedia.org/wiki/File:Neurofibroma_(3).jpg Neurofibroma - high mag. (WC)]. | *[http://commons.wikimedia.org/wiki/File:Neurofibroma_(3).jpg Neurofibroma - high mag. (WC)]. | ||
===IHC=== | |||
Features:<ref name=pmid12692193>{{cite journal |author=Hirose T, Tani T, Shimada T, Ishizawa K, Shimada S, Sano T |title=Immunohistochemical demonstration of EMA/Glut1-positive perineurial cells and CD34-positive fibroblastic cells in peripheral nerve sheath tumors |journal=Mod. Pathol. |volume=16 |issue=4 |pages=293–8 |year=2003 |month=April |pmid=12692193 |doi=10.1097/01.MP.0000062654.83617.B7 |url=http://www.nature.com/modpathol/journal/v16/n4/full/3880761a.html }}</ref> | |||
*S100 +ve. | |||
*CD34 +ve. | |||
*Glut1 +ve. | |||
*EMA +ve/-ve. | |||
==Malignant peripheral nerve sheath tumours== | ==Malignant peripheral nerve sheath tumours== | ||