Difference between revisions of "Nodular hyperplasia of the prostate gland"

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*Stromal and/or glandular hyperplasia.
*Stromal and/or glandular hyperplasia.


Note:
Notes:
*Should '''not''' be diagnosed on core biopsy!
*Should '''not''' be diagnosed on core biopsy!
*Cancer rates varies substaintially in resections done for BPH.
**One series suggests clinically relevant prostate cancer is seen in ~1.5% of cases.<ref>{{Cite journal  | last1 = Skrzypczyk | first1 = MA. | last2 = Dobruch | first2 = J. | last3 = Nyk | first3 = L. | last4 = Szostek | first4 = P. | last5 = Szempliński | first5 = S. | last6 = Borówka | first6 = A. | title = Should all specimens taken during surgical treatment of patients with benign prostatic hyperplasia be assessed by a pathologist? | journal = Cent European J Urol | volume = 67 | issue = 3 | pages = 227-32 | month =  | year = 2014 | doi = 10.5173/ceju.2014.03.art2 | PMID = 25247076 }}</ref>


DDx:
DDx:
*[[Urothelial carcinoma]] - significant nuclear atypia.
*[[Urothelial carcinoma]] - significant nuclear atypia.
*[[Prostate carcinoma]] - especially low-grade.
*[[Prostate carcinoma]] - especially low-grade.
**Approximately 17% of TURP specimens have cancer based on a series of 747 specimens.<ref name=pmid18684032>{{Cite journal  | last1 = Trpkov | first1 = K. | last2 = Thompson | first2 = J. | last3 = Kulaga | first3 = A. | last4 = Yilmaz | first4 = A. | title = How much tissue sampling is required when unsuspected minimal prostate carcinoma is identified on transurethral resection? | journal = Arch Pathol Lab Med | volume = 132 | issue = 8 | pages = 1313-6 | month = Aug | year = 2008 | doi = 10.1043/1543-2165(2008)132[1313:HMTSIR]2.0.CO;2 | PMID = 18684032 }}</ref>


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