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Difference between revisions of "Desmoid-type fibromatosis"
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Desmoid-type fibromatosis (view source)
Revision as of 23:39, 9 October 2014
, 23:39, 9 October 2014→Molecular
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**β-catenin accumulates in the nucleus. | **β-catenin accumulates in the nucleus. | ||
*Loss of function mutation in the APC gene. | *Loss of function mutation in the APC gene. | ||
**~15% of sporadic desmoids. | **~15% of sporadic desmoids.<ref name=pmid23020601/> | ||
** All familial adenomatous polyposis associated desmoids. | ** All familial adenomatous polyposis associated desmoids. | ||
**APC product unavailable to interact with β-catenin.<ref>URL: [http://ghr.nlm.nih.gov/condition/desmoid-tumor http://ghr.nlm.nih.gov/condition/desmoid-tumor]. Accessed on: 4 October 2014.</ref> | **APC product unavailable to interact with β-catenin.<ref>URL: [http://ghr.nlm.nih.gov/condition/desmoid-tumor http://ghr.nlm.nih.gov/condition/desmoid-tumor]. Accessed on: 4 October 2014.</ref> | ||