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Difference between revisions of "TFEB-rearranged renal cell carcinoma"
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TFEB-rearranged renal cell carcinoma (view source)
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'''Renal tumour with t(6;11) translocation''', also '''t(6,11) renal cell carcinoma''', is a rare [[kidney tumour]] seen primarily in children. | |||
==General== | |||
*Not common. | |||
*[[Lymph node metastases]] are common. | |||
*Essentially a pediatric tumour - case report of an adult.<ref name=pmid21884304>{{Cite journal | last1 = Ishihara | first1 = A. | last2 = Yamashita | first2 = Y. | last3 = Takamori | first3 = H. | last4 = Kuroda | first4 = N. | title = Renal carcinoma with (6;11)(p21;q12) translocation: Report of an adult case. | journal = Pathol Int | volume = 61 | issue = 9 | pages = 539-45 | month = Sep | year = 2011 | doi = 10.1111/j.1440-1827.2011.02711.x | PMID = 21884304 }}</ref> | |||
==Microscopic== | |||
Features: | |||
*Hyaline material between nests. | |||
*Large cells with clear to eosinophilic cytoplasm. | |||
==Molecular== | |||
*t(6;11)(p21;q12) Alpha/TFEB.<ref name=Ref_WMSP281>{{Ref WMSP|281}}</ref> | |||
==See also== | |||
*[[Kidney tumours]]. | |||
*[[Chromosomal translocations]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Kidney tumours]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||