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Difference between revisions of "Desmoid-type fibromatosis"
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Desmoid-type fibromatosis (view source)
Revision as of 10:05, 4 October 2014
, 10:05, 4 October 2014→Molecular
m (→Molecular) |
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**β-catenin accumulates in the nucleus. | **β-catenin accumulates in the nucleus. | ||
*Loss of function mutation in the APC gene. | *Loss of function mutation in the APC gene. | ||
**~15% of sporadic desmoids | **~15% of sporadic desmoids. | ||
** All familial adenomatous polyposis associated desmoids. | ** All familial adenomatous polyposis associated desmoids. | ||
**APC product unavailable to interact with β-catenin. | **APC product unavailable to interact with β-catenin. | ||