Difference between revisions of "Pityriasis rubra pilaris"

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| Caption    =  
| Caption    =  
| Synonyms  =
| Synonyms  =
| Micro      = alterating [[orthokeratosis]] and [[parakeratosis]] (known as "checkerboard pattern"), marked uniform acanthosis with broad dermal papillae and broad epidermal ridges, , +/-eosinophils (common), follicular plugging, scattered foci of [[acantholysis]] (common), occasional mild spongiosis
| Micro      = alterating [[orthokeratosis]] and [[parakeratosis]] (known as "checkerboard pattern"), marked uniform [[acanthosis]] with broad dermal papillae and broad epidermal ridges, , +/-eosinophils (common), follicular plugging, scattered foci of [[acantholysis]] (common), occasional mild spongiosis
| Subtypes  =
| Subtypes  =
| LMDDx      = [[Dermatomycosis|fungal infection]], Psoriasis, Darier disease, seborrhoeic dermatitis
| LMDDx      = [[Dermatomycosis|fungal infection]], Psoriasis, Darier disease, seborrhoeic dermatitis
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| Assdx      = HIV infection - recalcitrant PRP
| Assdx      = HIV infection - recalcitrant PRP
| Syndromes  =
| Syndromes  =
| Clinicalhx =Classic adult - self-limited exfoliative, erythematous dermatitis that starts over the head and neck and extends downwards forming orange plaques with spared islands of normal skin, follicular hyperkeratosis, palmar involvement with orange hyperkeratosis.
| Clinicalhx = Classic adult - self-limited exfoliative, erythematous dermatitis that starts over the head and neck and extends downwards forming orange plaques with spared islands of normal skin, follicular hyperkeratosis, palmar involvement with orange hyperkeratosis.
| Signs      =
| Signs      =
| Symptoms  =
| Symptoms  =
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Features:<ref name=pmid24783259>{{Cite journal  | last1 = Marrouche | first1 = N. | last2 = Kurban | first2 = M. | last3 = Kibbi | first3 = AG. | last4 = Abbas | first4 = O. | title = Pityriasis rubra pilaris: clinicopathological study of 32 cases from Lebanon. | journal = Int J Dermatol | volume = 53 | issue = 4 | pages = 434-9 | month = Apr | year = 2014 | doi =  | PMID = 24783259 }}</ref>
Features:<ref name=pmid24783259>{{Cite journal  | last1 = Marrouche | first1 = N. | last2 = Kurban | first2 = M. | last3 = Kibbi | first3 = AG. | last4 = Abbas | first4 = O. | title = Pityriasis rubra pilaris: clinicopathological study of 32 cases from Lebanon. | journal = Int J Dermatol | volume = 53 | issue = 4 | pages = 434-9 | month = Apr | year = 2014 | doi =  | PMID = 24783259 }}</ref>
*Alterating [[orthokeratosis]] and [[parakeratosis]] - known as "checkerboard pattern".
*Alterating [[orthokeratosis]] and [[parakeratosis]] - known as "checkerboard pattern".
*Marked uniform [[acanthosis]] with broad dermal papillae and broad epidermal ridges
*Follicular plugging.
*+/-Eosinophils (common).
*+/-Eosinophils (common).
*Follicular plugging.
*Scattered foci of [[Acantholysis]].<ref name=pmid23286804/>
*[[Acantholysis]].<ref name=pmid23286804/>


DDx:
DDx:
*[[Dermatomycosis|Fungal infection]].
*[[Dermatophyosis|Fungal infection]].
*Psoriasis vulgaris.<ref name=pmid18418089>{{Cite journal  | last1 = Brinster | first1 = NK. | title = Dermatopathology for the surgical pathologist: a pattern based approach to the diagnosis of inflammatory skin disorders (part I). | journal = Adv Anat Pathol | volume = 15 | issue = 2 | pages = 76-96 | month = Mar | year = 2008 | doi = 10.1097/PAP.0b013e3181664e8d | PMID = 18418089 }}</ref>
*Psoriasis vulgaris.<ref name=pmid18418089>{{Cite journal  | last1 = Brinster | first1 = NK. | title = Dermatopathology for the surgical pathologist: a pattern based approach to the diagnosis of inflammatory skin disorders (part I). | journal = Adv Anat Pathol | volume = 15 | issue = 2 | pages = 76-96 | month = Mar | year = 2008 | doi = 10.1097/PAP.0b013e3181664e8d | PMID = 18418089 }}</ref>
*Darier disease.
*Seborrhoeic dermatitis.


===Images===
===Images===
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