48,830
edits
Difference between revisions of "Rhabdomyosarcoma"
Jump to navigation
Jump to search
→Molecular diagnostics
(→IHC) |
|||
| Line 224: | Line 224: | ||
*t(1,13) vs. t(2,13) -- t(1,13) usually: younger age, extremity lesion, localized disease, better survival. | *t(1,13) vs. t(2,13) -- t(1,13) usually: younger age, extremity lesion, localized disease, better survival. | ||
*Several uncommon [[translocations]] exist. | *Several uncommon [[translocations]] exist. | ||
*In the [[urinary bladder]] of adults, the presence of a translocation is more-or-less required for the diagnosis of RMS.<ref name=pmid21762516>{{Cite journal | last1 = Bing | first1 = Z. | last2 = Zhang | first2 = PJ. | title = Adult urinary bladder tumors with rhabdomyosarcomatous differentiation: clinical, pathological and immunohistochemical studies. | journal = Diagn Pathol | volume = 6 | issue = | pages = 66 | month = | year = 2011 | doi = 10.1186/1746-1596-6-66 | PMID = 21762516 }}</ref> | |||
**It is suggested that keratin negative tumours without molecular testing to corroborate the impression of RMS be referred to as ''rhabdomyomatous tumours''.<ref name=pmid21762516/> | |||
===Embryonal rhabdomyosarcoma=== | ===Embryonal rhabdomyosarcoma=== | ||