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[[Image:Colon cancer 2.jpg|thumb|300px|[[Gross]] image of a [[colon cancer]].]] | [[Image:Colon cancer 2.jpg|thumb|300px|[[Gross]] image of a [[colon cancer]].]] | ||
'''Cancer''' is a leading cause of mortality and morbidity. It keeps pathologists busy. | '''Cancer''' is a leading cause of mortality and morbidity. It is what keeps pathologists busy. | ||
This article deals with general concepts in cancer. Specific forms of cancer are | This article deals with general concepts in cancer. Specific forms of cancer are dealt with in the site articles, e.g. esophageal cancer is dealt with in the ''[[esophagus]]'' article. | ||
In addition to be an introduction to cancer, this article also deals with ''cancers of unknown primary''. | |||
==Definition of cancer== | ==Definition of cancer== | ||
Robbins definition of cancer:<ref name=Ref_PCPBoD8_145>{{Ref PCPBoD8|145}}</ref> | The ''Robbins'' definition of cancer:<ref name=Ref_PCPBoD8_145>{{Ref PCPBoD8|145}}</ref> | ||
*Tumour with the capacity to: | *Tumour with the capacity to: | ||
*#Invade (infiltrate) and destroy adjacent tissue. | *#Invade (infiltrate) and destroy adjacent tissue. | ||
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===Tumours=== | ===Tumours=== | ||
Tumours '' | Tumours per ''Robbins''<ref name=Ref_PCPBoD8_145>{{Ref PCPBoD8|145}}</ref> consist of: | ||
#Clonal expansions. | #Clonal expansions. | ||
#Stromal components - controlled by the clonal component. | #Stromal components - controlled by the clonal component. |
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