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Difference between revisions of "Chondro-osseous tumours"
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→Chondroblastoma: more
(→Cartilage: +chondroblastoma) |
(→Chondroblastoma: more) |
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| Line 74: | Line 74: | ||
===Microscopic=== | ===Microscopic=== | ||
Features:<ref name=Ref_WMSP_642>{{Ref WMSP|642}}</ref> | Features:<ref name=Ref_WMSP_642>{{Ref WMSP|642}}</ref> | ||
*Abundant extracellular material - pink on [[H&E stain]]. | *Abundant extracellular material - pink on [[H&E stain]] - looks vaguely like cartilage. | ||
*Nuclear morphology variable: ovoid, folded or grooved. | *Chondroblasts: | ||
*+/-Calcifications | **Nuclear morphology variable: ovoid, folded or grooved. | ||
**Moderate-abundant eosinophilic cytoplasm. | |||
*+/-Calcifications surround cells nests ("chickenwire" appearance) - '''classic feature'''. | |||
*+/-Giant cells. | *+/-Giant cells. | ||
**May lead to confusion with ''giant cell tumour''. | **May lead to confusion with ''giant cell tumour''. | ||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Chondroblastoma_-_intermed_mag.jpg Chondroblastoma - intermed. mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Chondroblastoma_-_very_high_mag.jpg Chondroblastoma - very high mag. (WC)]. | |||
*[http://img.medscape.com/pi/emed/ckb/orthopedic_surgery/1230552-1254949-996.jpg Chondroblastoma (medscape.com)].<ref name=emed_chondroblastoma>URL: [http://emedicine.medscape.com/article/1254949-diagnosis http://emedicine.medscape.com/article/1254949-diagnosis]. Accessed on: 31 December 2010.</ref> | |||
*[http://img.medscape.com/pi/emed/ckb/orthopedic_surgery/1230552-1254949-997.jpg Chondroblastoma with "chickenwire" appearance (medscape.com)].<ref name=emed_chondroblastoma>URL: [http://emedicine.medscape.com/article/1254949-diagnosis http://emedicine.medscape.com/article/1254949-diagnosis]. Accessed on: 31 December 2010.</ref> | |||
===IHC=== | ===IHC=== | ||
Features:<ref name=Ref_WMSP_642>{{Ref WMSP|642}}</ref> | Features:<ref name=Ref_WMSP_642>{{Ref WMSP|642}}</ref> | ||
*S100 +ve. | *S100 +ve. | ||
*Vimentin +ve.<ref name=emed_chondroblastoma>URL: [http://emedicine.medscape.com/article/1254949-diagnosis http://emedicine.medscape.com/article/1254949-diagnosis]. Accessed on: 31 December 2010.</ref> | |||
==Chondrosarcoma== | ==Chondrosarcoma== | ||