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Difference between revisions of "Paget's disease of the breast"
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Paget's disease of the breast (view source)
Revision as of 02:12, 11 September 2014
, 02:12, 11 September 2014no edit summary
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'''[[Paget's disease]] of the breast''', also '''Paget disease of the breast''' and '''Paget's disease of the nipple''', is a lesion of the [[breast]]. It is abbreviated '''PDB'''.<ref name=pmid19919588>{{Cite journal | last1 = Ellis | first1 = PE. | last2 = Maclean | first2 = AB. | last3 = Crow | first3 = JC. | last4 = Wong Te Fong | first4 = LF. | last5 = Rolfe | first5 = KJ. | last6 = Perrett | first6 = CW. | title = Expression of cyclin D1 and retinoblastoma protein in Paget's disease of the vulva and breast: an immunohistochemical study of 108 cases. | journal = Histopathology | volume = 55 | issue = 6 | pages = 709-15 | month = Dec | year = 2009 | doi = 10.1111/j.1365-2559.2009.03434.x | PMID = 19919588 }}</ref> | '''[[Paget's disease]] of the breast''', also '''Paget disease of the breast''' and '''Paget's disease of the nipple''', is a lesion of the [[breast]]. It is abbreviated '''PDB'''.<ref name=pmid19919588>{{Cite journal | last1 = Ellis | first1 = PE. | last2 = Maclean | first2 = AB. | last3 = Crow | first3 = JC. | last4 = Wong Te Fong | first4 = LF. | last5 = Rolfe | first5 = KJ. | last6 = Perrett | first6 = CW. | title = Expression of cyclin D1 and retinoblastoma protein in Paget's disease of the vulva and breast: an immunohistochemical study of 108 cases. | journal = Histopathology | volume = 55 | issue = 6 | pages = 709-15 | month = Dec | year = 2009 | doi = 10.1111/j.1365-2559.2009.03434.x | PMID = 19919588 }}</ref> | ||
There is also a ''[[Paget disease of the bone]]'' - just to make things confusing. This is dealt with in the ''[[bone]]'' article and has nothing (from a pathologic perspective) to do with the Paget disease discussed in this article; these two things just happened to be discovered by the same guy. | There is also a ''[[Paget's disease of the bone]]'' - just to make things confusing. This is dealt with in the ''[[bone]]'' article and has nothing (from a pathologic perspective) to do with the Paget disease discussed in this article; these two things just happened to be discovered by the same guy. | ||
Non-bone Paget disease is subdivided into: | Non-bone Paget's disease is subdivided into: | ||
#Mammary Paget disease - dealt with in this article. | #Mammary Paget's disease - dealt with in this article. | ||
#[[Extramammary Paget disease]]. | #[[Extramammary Paget's disease]]. | ||
Histologically, i.e. under the [[microscope]], the above are essentially identically; however, the associations (and prognosis) are quite different! | Histologically, i.e. under the [[microscope]], the above are essentially identically; however, the associations (and prognosis) are quite different! | ||