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Difference between revisions of "KRAS mutation"
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[[Image:Colonic mucinous adenocarcinoma - low mag.jpg|thumb|right|[[Micrograph]] showing mucinous carcinoma, a histology associated with KRAS mutations.]] | |||
'''KRAS mutation''' is a re-occuring theme in [[molecular pathology]]. KRAS is an [[oncogene]].<ref name=omim190070>{{OMIM|190070}}</ref> | '''KRAS mutation''' is a re-occuring theme in [[molecular pathology]]. KRAS is an [[oncogene]].<ref name=omim190070>{{OMIM|190070}}</ref> | ||
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==Microscopic== | ==Microscopic== | ||
Features: | Features: | ||
*Typically [[mucinous carcinoma]]. | *Typically [[mucinous carcinoma]].<ref name=pmid25029118>{{Cite journal | last1 = Kadota | first1 = K. | last2 = Yeh | first2 = YC. | last3 = D'Angelo | first3 = SP. | last4 = Moreira | first4 = AL. | last5 = Kuk | first5 = D. | last6 = Sima | first6 = CS. | last7 = Riely | first7 = GJ. | last8 = Arcila | first8 = ME. | last9 = Kris | first9 = MG. | title = Associations between mutations and histologic patterns of mucin in lung adenocarcinoma: invasive mucinous pattern and extracellular mucin are associated with KRAS mutation. | journal = Am J Surg Pathol | volume = 38 | issue = 8 | pages = 1118-27 | month = Aug | year = 2014 | doi = 10.1097/PAS.0000000000000246 | PMID = 25029118 }}</ref> | ||
==See also== | ==See also== | ||