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Difference between revisions of "Small intestine"
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note about IHC
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(note about IHC) |
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The '''small bowel''' is a relatively well-behaved piece of machinery from the perspective of pathology. It is uncommonly affected by malignancies. | The '''small bowel''' is a relatively well-behaved piece of machinery from the perspective of pathology. It is uncommonly affected by malignancies. | ||
==Anatomy== | ==Anatomy== | ||
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In the context of bowel obstructions and IBD, pathologists often see resected stomas (that were put in place emergently). These specimens are usually fairly straight forward. | In the context of bowel obstructions and IBD, pathologists often see resected stomas (that were put in place emergently). These specimens are usually fairly straight forward. | ||
==[[Immunohistochemistry]]== | |||
*Normal small intestine is CK20 +ve... while adenocarcinoma of the small bowel may be CK20 -ve.<ref>{{cite journal |author=Chen ZM, Wang HL |title=Alteration of cytokeratin 7 and cytokeratin 20 expression profile is uniquely associated with tumorigenesis of primary adenocarcinoma of the small intestine |journal=Am. J. Surg. Pathol. |volume=28 |issue=10 |pages=1352–9 |year=2004 |month=October |pmid=15371952 |doi= |url=}}</ref> | |||
==Histology== | ==Histology== | ||