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Difference between revisions of "Immunohistochemical staining"
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Immunohistochemical staining (view source)
Revision as of 01:50, 15 August 2014
, 01:50, 15 August 2014→General (malignant) differential diagnosis
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***Many pathologists think this stain is totally useless. | ***Many pathologists think this stain is totally useless. | ||
*Germ cell tumours. | *Germ cell tumours. | ||
**PLAP (placental-like alkaline phosphatase) - not very sensitive.<ref name=pmid18045648>{{cite journal |author=Iczkowski KA, Butler SL, Shanks JH, ''et al'' |title=Trials of new germ cell immunohistochemical stains in 93 extragonadal and metastatic germ cell tumors |journal=Hum. Pathol. |volume=39 |issue=2 |pages=275-81 |year=2008 |month=February |pmid=18045648 |doi=10.1016/j.humpath.2007.07.002 |url=}}</ref> | **OCT4. | ||
** | ***PLAP ([[placental-like alkaline phosphatase]]) - not very sensitive.<ref name=pmid18045648>{{cite journal |author=Iczkowski KA, Butler SL, Shanks JH, ''et al'' |title=Trials of new germ cell immunohistochemical stains in 93 extragonadal and metastatic germ cell tumors |journal=Hum. Pathol. |volume=39 |issue=2 |pages=275-81 |year=2008 |month=February |pmid=18045648 |doi=10.1016/j.humpath.2007.07.002 |url=}}</ref> | ||
**Glypican 3 +ve. | |||
*Neuroendocrine carcinoma. | *Neuroendocrine carcinoma. | ||
**Chromogranin A. | **Chromogranin A. | ||