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Difference between revisions of "Prostate cancer"
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→Prostate markers
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*Prostate carcinoma is typically CK7 -ve and CK20 -ve; however, high Gleason score cancers focal positivity of these markers can be seen.<ref name=pmid11888088>{{Cite journal | last1 = Goldstein | first1 = NS. | title = Immunophenotypic characterization of 225 prostate adenocarcinomas with intermediate or high Gleason scores. | journal = Am J Clin Pathol | volume = 117 | issue = 3 | pages = 471-7 | month = Mar | year = 2002 | doi = 10.1309/G6PR-Y774-X738-FG2K | PMID = 11888088 }}</ref> | *Prostate carcinoma is typically CK7 -ve and CK20 -ve; however, high Gleason score cancers focal positivity of these markers can be seen.<ref name=pmid11888088>{{Cite journal | last1 = Goldstein | first1 = NS. | title = Immunophenotypic characterization of 225 prostate adenocarcinomas with intermediate or high Gleason scores. | journal = Am J Clin Pathol | volume = 117 | issue = 3 | pages = 471-7 | month = Mar | year = 2002 | doi = 10.1309/G6PR-Y774-X738-FG2K | PMID = 11888088 }}</ref> | ||
**CK7: >25-50% staining seen in ~5% of cases. | **CK7: >25-50% staining seen in ~5% of cases. | ||
***>50% | ***>50% staining with CK7 is not report. | ||
**CK20: >25-50% staining seen in ~10% of cases. | **CK20: >25-50% staining seen in ~10% of cases. | ||
***>50% staining with CK20 is not reported. | ***>50% staining with CK20 is not reported. | ||