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Difference between revisions of "Serous carcinoma of the ovary"
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Serous carcinoma of the ovary (view source)
Revision as of 20:13, 15 July 2014
, 20:13, 15 July 2014no edit summary
| Line 11: | Line 11: | ||
| IHC = WT-1 +ve, CK7 +ve, ER +ve, HNF-1beta -ve | | IHC = WT-1 +ve, CK7 +ve, ER +ve, HNF-1beta -ve | ||
| EM = | | EM = | ||
| Molecular = | | Molecular = +/-BRCA1 mutation, +/-BRCA2 mutation | ||
| IF = | | IF = | ||
| Gross = solid and cystic, serous fluid | | Gross = solid and cystic, serous fluid | ||
| Line 35: | Line 35: | ||
*Most common malignant ovarian tumour in the eldery. | *Most common malignant ovarian tumour in the eldery. | ||
*Poor prognosis. | *Poor prognosis. | ||
*May be associated with a ''[[BRCA1]] gene'' or ''BRACA2 gene'' mutation.<ref name=pmid23707676>{{Cite journal | last1 = Demsky | first1 = R. | last2 = McCuaig | first2 = J. | last3 = Maganti | first3 = M. | last4 = Murphy | first4 = KJ. | last5 = Rosen | first5 = B. | last6 = Armel | first6 = SR. | title = Keeping it simple: genetics referrals for all invasive serous ovarian cancers. | journal = Gynecol Oncol | volume = 130 | issue = 2 | pages = 329-33 | month = Aug | year = 2013 | doi = 10.1016/j.ygyno.2013.05.003 | PMID = 23707676 }}</ref> | *May be associated with a ''[[BRCA1]] gene'' or ''[[BRACA2]] gene'' mutation.<ref name=pmid23707676>{{Cite journal | last1 = Demsky | first1 = R. | last2 = McCuaig | first2 = J. | last3 = Maganti | first3 = M. | last4 = Murphy | first4 = KJ. | last5 = Rosen | first5 = B. | last6 = Armel | first6 = SR. | title = Keeping it simple: genetics referrals for all invasive serous ovarian cancers. | journal = Gynecol Oncol | volume = 130 | issue = 2 | pages = 329-33 | month = Aug | year = 2013 | doi = 10.1016/j.ygyno.2013.05.003 | PMID = 23707676 }}</ref> | ||
Precursors lesions: | Precursors lesions: | ||