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| *[[AKA]] ''lichen planus-like keratosis''. | | *[[AKA]] ''lichen planus-like keratosis''. |
| *[[AKA]] ''lichenoid keratosis''. | | *[[AKA]] ''lichenoid keratosis''. |
| | | {{Main|Lichenoid keratosis}} |
| ===General===
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| *Caucasians - middle age or older.
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| *May be a variant of [[seborrheic keratosis]] (with marked inflammation).<ref name=Ref_Derm346>{{Ref Derm|346}}</ref>
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| Clinical DDx:<ref name=Ref_Derm346>{{Ref Derm|346}}</ref>
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| *[[Basal cell carcinoma]], [[squamous cell carcinoma of the skin]], melanocytic neoplasm.
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| | |
| ===Microscopic===
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| Features:<ref name=Ref_Derm347>{{Ref Derm|347}}</ref>
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| *Hyperkeratosis.
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| *Parakeratosis.
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| *Band of inflammatory cells at DE junction (lichenoid inflammation).
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| *Dead keratinocytes (Civatte bodies).
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| *Dermal melanophages.
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| DDx:
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| *[[Lichen planus]] - need clinical correlation (mucosal lesions).
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| *[[Drug reaction]].
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| *[[Cutaneous T-cell lymphoma]].
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| *Regressed melanocytic lesion, esp. [[malignant melanoma]].
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| *Lichenoid [[actinic keratosis]] - has atypical hyperchromatic basal cells - esp. at edge of lesion, usu. in the context of [[solar elastosis]].
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| Images:
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| *[http://www.dermpathexpert.com/id57.html Lichenoid keratosis (dermpathexpert.com)].
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| ===Sign out===
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| <pre>
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| SKIN LESION, MID-MIDDLE BACK, PUNCH BIOPSY:
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| - LICHENOID KERATOSIS.
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| </pre>
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| ====Incompletely excised====
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| <pre>
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| SKIN LESION, LEFT CHEST, PUNCH BIOPSY:
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| - LICHENOID KERATOSIS VERSUS ACTINIC KERATOSIS.
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| - NEGATIVE FOR BASAL CELL CARCINOMA.
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| - SEE COMMENT.
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| COMMENT:
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| No eosinophils are apparent. No melanocytic lesion is identified; however, excision of the
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| whole lesion to exclude a partially regressed melanocytic lesion is suggested.
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| </pre>
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| ==Granuloma annulare== | | ==Granuloma annulare== |