Difference between revisions of "Pseudoepitheliomatous hyperplasia"

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'''Pseudoepitheliomatous hyperplasia''', abbreviated '''PEH''', is a benign reactive change that can mimic [[squamous cell carcinoma]].
'''Pseudoepitheliomatous hyperplasia''', abbreviated '''PEH''', is a benign reactive change of squamous mucosa that can mimic [[squamous cell carcinoma]].
 
==General==
*Benign.
*Not common.


It is seen in:
It is seen in:
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#Adjacent to an ulcer.
#Adjacent to an ulcer.
#*May form after an injury to the skin.<ref name=pmid17244318>{{Cite journal  | last1 = Fu | first1 = X. | last2 = Jiang | first2 = D. | last3 = Chen | first3 = W. | last4 = Sun Bs | first4 = T. | last5 = Sheng | first5 = Z. | title = Pseudoepitheliomatous hyperplasia formation after skin injury. | journal = Wound Repair Regen | volume = 15 | issue = 1 | pages = 39-46 | month =  | year =  | doi = 10.1111/j.1524-475X.2006.00183.x | PMID = 17244318 }}</ref>
#*May form after an injury to the skin.<ref name=pmid17244318>{{Cite journal  | last1 = Fu | first1 = X. | last2 = Jiang | first2 = D. | last3 = Chen | first3 = W. | last4 = Sun Bs | first4 = T. | last5 = Sheng | first5 = Z. | title = Pseudoepitheliomatous hyperplasia formation after skin injury. | journal = Wound Repair Regen | volume = 15 | issue = 1 | pages = 39-46 | month =  | year =  | doi = 10.1111/j.1524-475X.2006.00183.x | PMID = 17244318 }}</ref>
==Microscopic==
==Microscopic==
Features:<ref name=pmid17614808>{{Cite journal  | last1 = Cui | first1 = W. | last2 = McGregor | first2 = DH. | last3 = Stark | first3 = SP. | last4 = Ulusarac | first4 = O. | last5 = Mathur | first5 = SC. | title = Pseudoepitheliomatous hyperplasia - an unusual reaction following tattoo: report of a case and review of the literature. | journal = Int J Dermatol | volume = 46 | issue = 7 | pages = 743-5 | month = Jul | year = 2007 | doi = 10.1111/j.1365-4632.2007.03150.x | PMID = 17614808 }}</ref>
Features:<ref name=pmid17614808>{{Cite journal  | last1 = Cui | first1 = W. | last2 = McGregor | first2 = DH. | last3 = Stark | first3 = SP. | last4 = Ulusarac | first4 = O. | last5 = Mathur | first5 = SC. | title = Pseudoepitheliomatous hyperplasia - an unusual reaction following tattoo: report of a case and review of the literature. | journal = Int J Dermatol | volume = 46 | issue = 7 | pages = 743-5 | month = Jul | year = 2007 | doi = 10.1111/j.1365-4632.2007.03150.x | PMID = 17614808 }}</ref>
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*Parakeratosis - nuclei in the stratum corneum.
*Parakeratosis - nuclei in the stratum corneum.


Images:
DDx:
*[[Squamous cell carcinoma]].
 
===Images===
*[http://www.pathologyoutlines.com/images/prostate/10_14.jpg Pseudoepitheliomatous hyperplasia (pathologyoutlines.com)].<ref>URL: [http://www.pathologyoutlines.com/topic/penscrotumpenssqhyper.html http://www.pathologyoutlines.com/topic/penscrotumpenssqhyper.html]. Accessed on: 10 November 2012.</ref>
*[http://www.pathologyoutlines.com/images/prostate/10_14.jpg Pseudoepitheliomatous hyperplasia (pathologyoutlines.com)].<ref>URL: [http://www.pathologyoutlines.com/topic/penscrotumpenssqhyper.html http://www.pathologyoutlines.com/topic/penscrotumpenssqhyper.html]. Accessed on: 10 November 2012.</ref>
*[http://www.the-dermatologist.com/sites/default/files/issues/January2012/Fungal%20Figure%204.png Pseudoepitheliomatous hyperplasia (the-dermatologist.com)].<ref>URL: [http://www.the-dermatologist.com/content/treating-rare-fungal-infections-coccidioidomycosis http://www.the-dermatologist.com/content/treating-rare-fungal-infections-coccidioidomycosis]. Accessed on: 10 November 2012.</ref>
*[http://www.the-dermatologist.com/sites/default/files/issues/January2012/Fungal%20Figure%204.png Pseudoepitheliomatous hyperplasia (the-dermatologist.com)].<ref>URL: [http://www.the-dermatologist.com/content/treating-rare-fungal-infections-coccidioidomycosis http://www.the-dermatologist.com/content/treating-rare-fungal-infections-coccidioidomycosis]. Accessed on: 10 November 2012.</ref>
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