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Difference between revisions of "Fibrous hamartoma of infancy"
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'''Fibrous hamartoma''' is an uncommon lesion | '''Fibrous hamartoma''' is an uncommon lesion usually seen in infancy. | ||
==General== | ==General== | ||
*Uncommon. | *Uncommon. | ||
*Infants. {{ | *Infants and young children.<ref name=pmid24525510>{{Cite journal | last1 = Saab | first1 = ST. | last2 = McClain | first2 = CM. | last3 = Coffin | first3 = CM. | title = Fibrous hamartoma of infancy: a clinicopathologic analysis of 60 cases. | journal = Am J Surg Pathol | volume = 38 | issue = 3 | pages = 394-401 | month = Mar | year = 2014 | doi = 10.1097/PAS.0000000000000104 | PMID = 24525510 }}</ref> | ||
==Gross== | |||
*Typical location: lower back, gluteal region or [[scrotum]].<ref name=pmid22066102/> | |||
==Microscopic== | ==Microscopic== | ||
Features: | Features:<ref name=pmid24525510/> | ||
*Fibrous tissue. | |||
*Adipose tissue. | *Adipose tissue. | ||
* | *Mesenchymal tissue - nerve-like. | ||
* | *+/-Pseudoangiomatous pattern. | ||
DDx: | DDx: | ||
*[[Neurofibroma]]. | *[[Neurofibroma]]. | ||
*[[GCT of the tendon shealth]]. | *[[GCT of the tendon shealth]]. | ||
===Images=== | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657246/figure/F1/ FH (nih.gov)].<ref name=pmid23716836>{{Cite journal | last1 = F-Eire | first1 = P. | last2 = Fojon | first2 = JG. | title = Cutaneous changes in fibrous hamartoma of infancy. | journal = Indian J Dermatol | volume = 58 | issue = 2 | pages = 160 | month = Mar | year = 2013 | doi = 10.4103/0019-5154.108089 | PMID = 23716836 }}</ref> | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204559/figure/F1/ FH (nih.gov)].<ref name=pmid22066102>{{Cite journal | last1 = Kang | first1 = G. | last2 = Suh | first2 = YL. | last3 = Han | first3 = J. | last4 = Kwon | first4 = GY. | last5 = Lee | first5 = SK. | last6 = Seo | first6 = JM. | title = Fibrous hamartoma of infancy: an experience of a single institute. | journal = J Korean Surg Soc | volume = 81 | issue = 1 | pages = 61-5 | month = Jul | year = 2011 | doi = 10.4174/jkss.2011.81.1.61 | PMID = 22066102 }}</ref> | |||
==IHC== | ==IHC== | ||
*S-100 -ve. | Features:<ref name=pmid24525510/> | ||
*S-100 -ve. | |||
**Adipose tissue +ve. | |||
*SMA +ve (fibrous tissue). | |||
*CD34 +ve (fibrous tissue, immature mesenchymal tissue, pseudoangiomatous foci). | |||
==See also== | |||
*[[Pediatric pathology]]. | |||
*[[Dermatopathology]]. | |||
==References== | |||
{{reflist|1}} | |||
[[Category:Dermatopathology]] | [[Category:Dermatopathology]] | ||