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'''Anovulatory endometrium''' is common perimenopausal finding. It is a diagnosis that is inferred from the clinical context. | |||
It may be used as a synonym for ''[[disordered proliferative endometrium]]'' (DPE). | |||
[[Libre Pathology]] separates the two. DPE has prominent gland dilation (reminiscent of [[simple endometrial hyperplasia]]) and may not have shedding. AV has shedding without gland dilation. | |||
==General== | |||
*Individuals usually perimenopausal. | |||
*May be used as a synonym for ''[[disordered proliferative phase]]''.<ref>URL: [http://www.surgpath4u.com/caseviewer.php?case_no=382 http://www.surgpath4u.com/caseviewer.php?case_no=382]. Accessed on: 9 May 2013.</ref> | |||
==Microscopic== | |||
Features: | |||
*Shedding: | |||
**Stromal condensation. | |||
**Apoptotic endometrial epithelium. | |||
*Weakly proliferative glands or non-proliferative glands. | |||
DDx: | |||
*[[Disordered proliferative phase]] - gland dilation. | |||
*[[Simple endometrial hyperplasia]]. | |||
*[[Menstrual endometrium]] - should have mitoses,<ref name=Ref_DCHH237>{{Ref DCHH|237}}</ref> abundant [[PMN]]s. | |||
==Sign out== | |||
<pre> | |||
ENDOMETRIUM, CURETTAGE: | |||
- FRAGMENTED PROLIFERATIVE ENDOMETRIUM WITH EVIDENCE OF SHEDDING, WITHOUT ABUNDANT | |||
NEUTROPHILS, SEE COMMENT. | |||
- NO EVIDENCE OF HYPERPLASIA. | |||
- NEGATIVE FOR MALIGNANCY. | |||
COMMENT: | |||
The changes are compatible with anovulatory bleeding. | |||
</pre> | |||
<pre> | |||
ENDOMETRIUM, CURETTAGE: | |||
- PROLIFERATIVE ENDOMETRIUM WITH SMALL ROUND GLANDS AND SHEDDING, SEE COMMENT. | |||
- BENIGN ENDOCERVICAL MUCOSA. | |||
- NEGATIVE FOR HYPERPLASIA. | |||
- NEGATIVE FOR MALIGNANCY. | |||
COMMENT: | |||
The changes are suggestive of anovulatory bleeding. | |||
</pre> | |||
<pre> | |||
ENDOMETRIUM, BIOPSY: | |||
- BENIGN ENDOCERVICAL POLYP WITH ACUTE AND CHRONIC INFLAMMATION, AND EVIDENCE | |||
SUGGESTIVE OF EROSIONS (SIDEROPHAGES, INCREASED BLOOD VESSEL DENSITY). | |||
- SMALL NONPROLIFERATIVE ENDOMETRIAL GLANDS WITH RARE NEUTROPHILS AND RARE | |||
APOPTOTIC CELLS, WITH BALLS OF CONDENSED ENDOMETRIAL STROMA, SEE COMMENT. | |||
- NEGATIVE FOR ENDOMETRIAL HYPERPLASIA AND NEGATIVE FOR DYSPLASIA. | |||
COMMENT: | |||
The changes are suggestive of anovulatory bleeding. | |||
</pre> | |||
<pre> | |||
ENDOMETRIUM, ASPIRATION: | |||
- PSEUDOSTRATIFIED ENDOMETRIAL EPITHELIUM WITHOUT APPARENT PROLIFERATION, WITH | |||
APOPTOTIC CELLS AND LIMITED STROMA WITH RARE (STROMAL) CONDENSATION -- COMPATIBLE | |||
WITH SHEDDING. | |||
- MINUTE FRAGMENTS OF BENIGN ENDOCERVICAL EPITHELIUM. | |||
- NO EVIDENCE OF HYPERPLASIA. | |||
</pre> | |||
==See also== | |||
*[[Endometrium]]. | |||
*[[Disordered proliferative endometrium]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Endometrium]] |
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