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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Degenerative joint disease - severe - alt -- low mag.jpg | |||
| Width = | |||
| Caption = Severe degenerative joint disease. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = vertical clefts of the cartilage, +/-thickening of [[bone|bony]] trabeculae, subchondral cysts (where there is cartilage loss), +/-mild inflammation (lymphocytes), +/-villous hyperplasia (synovium has finger-like projections into the joint space), osteophytes (ossified projections at the edge of the articular cartilage) | |||
| Subtypes = | |||
| LMDDx = [[rheumatoid arthritis]], infectious arthritis, arthritis secondary to other disease (IBD, rheumatologic condition), trauma/deformity related, [[AVN]]-related | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = thinning/loss of cartilage, osteophyte formation, subchondral cysts, subchondral sclerosis | |||
| Grossing = | |||
| Site = [[joints]], e.g. [[femoral head]], knee, shoulder | |||
| Assdx = trauma to joint, [[obesity]] (for knees), congenital disease ([[SCFE]], [[Legg–Calvé–Perthes disease]]), complication of [[avascular necrosis of the femoral head]] | |||
| Syndromes = | |||
| Clinicalhx = old age | |||
| Signs = joint pain | |||
| Symptoms = | |||
| Prevalence = very common | |||
| Bloodwork = | |||
| Rads = joint space narrowing, osteophyte formation, subchondral cysts, subchondral sclerosis | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = other types of [[arthritis]] | |||
| Tx = pain medications, joint replacement | |||
}} | |||
'''Osteoarthritis''', abbreviated '''OA''', is a degenerative disease of the joint. | '''Osteoarthritis''', abbreviated '''OA''', is a degenerative disease of the joint. | ||
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