48,830
edits
Difference between revisions of "Phosphaturic mesenchymal tumour, mixed connective tissue type"
Jump to navigation
Jump to search
Phosphaturic mesenchymal tumour, mixed connective tissue type (view source)
Revision as of 19:55, 12 June 2014
, 19:55, 12 June 2014no edit summary
(more) |
|||
| Line 44: | Line 44: | ||
==Microscopic== | ==Microscopic== | ||
Features:<ref name=pmid22927293/><ref name=pmid19828339/> | Features:<ref name=pmid22927293/><ref name=pmid19828339/> | ||
*Spindle cells without atypia | *Spindle cells without atypia and moderate lightly eosinophilic cytoplasm without distinctive cell borders. | ||
*Eosinophilic matrix - described as "gungy" (shabby).<ref name=pmid14707860/> | |||
*[[HPC-like vessels]]. | |||
*Osteoclast-type [[giant cell]]s. | *Osteoclast-type [[giant cell]]s. | ||
*+/-Hemorrhage. | |||
*+/-Calcifications. | *+/-Calcifications. | ||
DDx: | |||
*[[Osteosarcoma]]. | DDx:<ref name=pmid14707860/> | ||
*[[Osteosarcoma]] - has cellular atypia. | |||
*[[Hemangiopericytoma]]. | |||
*[[Giant cell tumour of bone]]. | |||
*[[Neurofibroma]]. | *[[Neurofibroma]]. | ||
*Other [[soft tissue lesions]]. | *Other [[soft tissue lesions]]. | ||
| Line 63: | Line 69: | ||
*S-100 -ve. | *S-100 -ve. | ||
*CD34 -ve. | *CD34 -ve. | ||
*FGF-23 +ve.<ref name=pmid14707860>{{cite journal |author=Folpe AL, Fanburg-Smith JC, Billings SD, ''et al.'' |title=Most osteomalacia-associated mesenchymal tumors are a single histopathologic entity: an analysis of 32 cases and a comprehensive review of the literature |journal=Am. J. Surg. Pathol. |volume=28 |issue=1 |pages=1–30 |year=2004 |month=January |pmid=14707860 |doi= |url=}}</ref> | |||
Others:<ref name=pmid22035861>{{cite journal |author=Hu FK, Yuan F, Jiang CY, ''et al.'' |title=Tumor-induced osteomalacia with elevated fibroblast growth factor 23: a case of phosphaturic mesenchymal tumor mixed with connective tissue variants and review of the literature |journal=Chin J Cancer |volume=30 |issue=11 |pages=794–804 |year=2011 |month=November |pmid=22035861 |pmc=4013303 |doi=10.5732/cjc.011.10013 |url=}}</ref> | Others:<ref name=pmid22035861>{{cite journal |author=Hu FK, Yuan F, Jiang CY, ''et al.'' |title=Tumor-induced osteomalacia with elevated fibroblast growth factor 23: a case of phosphaturic mesenchymal tumor mixed with connective tissue variants and review of the literature |journal=Chin J Cancer |volume=30 |issue=11 |pages=794–804 |year=2011 |month=November |pmid=22035861 |pmc=4013303 |doi=10.5732/cjc.011.10013 |url=}}</ref> | ||