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===Provided clinical history=== | ===Provided clinical history=== | ||
64 year old man, renal mass | |||
===Site=== | ===Site=== | ||
right kidney (nephrectomy) | |||
===Primary image=== | ===Primary image=== | ||
[[Image: | [[Image: Papillary_renal_cell_carcinoma_-_2_--_intermed_mag.jpg|500px|link=|center|]] | ||
<center> | <center>Intermediate magnification. [[H&E stain]].</center> | ||
{{hidden| | {{hidden|High magnification|[[Image: Papillary_renal_cell_carcinoma_-_2_--_high_mag.jpg |500px|link=|center|]] | ||
<center>High magnification. [[H&E stain]].</center>}} | <center>High magnification. [[H&E stain]].</center>}} | ||
{{hidden|Very high magnification|[[Image: Papillary_renal_cell_carcinoma_-_2_--_very_high_mag.jpg |500px|link=|center|]] | |||
<center>Very high magnification. [[H&E stain]].</center>}} | |||
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===Differential diagnosis=== | ===Differential diagnosis=== | ||
{{hidden|Differential diagnosis|<center> | {{hidden|Differential diagnosis|<center></center>}} | ||
--> | |||
===Additional tests=== | ===Additional tests=== | ||
====More history==== | ====More history==== | ||
{{hidden|More history|<center> | {{hidden|More history|<center>Smoker. Fell and broke back. CT scan found an incidental 3.7 cm renal mass.</center>}} | ||
====Ask a colleague==== | ====Ask a colleague==== | ||
{{hidden|Ask a colleague|<center> | {{hidden|Ask a colleague|<center>Looks low grade. I bet it would be CK7+ and AMACR+... not that those are needed.</center>}} | ||
====Stains==== | ====Stains==== | ||
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| afp= | | afp= | ||
| alk1= | | alk1= | ||
| amacr= | | amacr= '''POSITIVE''' | ||
| ar= | | ar= | ||
| b2microglobulin= | | b2microglobulin= | ||
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| calretinin= | | calretinin= | ||
| cam5p2= | | cam5p2= | ||
| cd10= | | cd10= '''POSITIVE''' | ||
| cd117= | | cd117= | ||
| cd138= | | cd138= | ||
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| cd56= | | cd56= | ||
| cd57= | | cd57= | ||
| cd68= | | cd68= '''POSITIVE''' in foamy cells | ||
| cd7= | | cd7= | ||
| cd79a= | | cd79a= | ||
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| ck34be12= | | ck34be12= | ||
| ck5_6= | | ck5_6= | ||
| ck7= | | ck7= '''POSITIVE''' | ||
| cmv= | | cmv= | ||
| cmyc= | | cmyc= | ||
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| vip= | | vip= | ||
| vzv= | | vzv= | ||
| wt1= | | wt1= '''NEGATIVE''' | ||
}} | }} | ||
====Chromosomal translocations==== | ====Chromosomal translocations==== | ||
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===Diagnosis=== | ===Diagnosis=== | ||
{{hidden|Diagnosis|<center> | {{hidden|Diagnosis|<center>[[Papillary renal cell carcinoma]], type 1</center>}} | ||
<br> | <br> | ||
===Other cases=== | ===Other cases=== | ||
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<!-- SELECT A CATEGORY | <!-- SELECT A CATEGORY | ||
[[Category:Cases in genitourinary pathology]] | [[Category:Cases in genitourinary pathology]] | ||
[[Category:Cases in genitourinary pathology - junior]] | |||
--> | --> | ||
[[Category:Cases difficulty | [[Category:Cases difficulty 2]] <!-- difficulty 1-7 -- should roughly correspond to the PGY level --> |
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