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Difference between revisions of "Medical liver disease"
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==Focal nodular hyperplasia== | ==Focal nodular hyperplasia== | ||
===General==== | |||
*Abbreviated ''FNH''. | *Abbreviated ''FNH''. | ||
*Not commonly seen by pathologists. | *Not commonly seen by pathologists. | ||
*Benign lesions. | *Benign lesions. | ||
*Associated with oral contraceptive pill (OCP) use. | *Associated with oral contraceptive pill (OCP) use. | ||
*May be seen in the context of [[hereditary hemorrhagic telangiectasia]].<ref name=pmid18814078>{{cite journal |author=Khalid SK, Garcia-Tsao G |title=Hepatic vascular malformations in hereditary hemorrhagic telangiectasia |journal=Semin. Liver Dis. |volume=28 |issue=3 |pages=247–58 |year=2008 |month=August |pmid=18814078 |doi=10.1055/s-0028-1085093 |url=}}</ref> | |||
===Imaging=== | ====Imaging==== | ||
*FNH enhances on the arterial phase in triphasic imaging, i.e. triphasic CT or MRI.<ref name=emedicine_fnh>[http://emedicine.medscape.com/article/368377-overview http://emedicine.medscape.com/article/368377-overview]</ref> | *FNH enhances on the arterial phase in triphasic imaging, i.e. triphasic CT or MRI.<ref name=emedicine_fnh>[http://emedicine.medscape.com/article/368377-overview http://emedicine.medscape.com/article/368377-overview]</ref> | ||
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Note: Usually a solitary lesion.<ref name=emedicine_fnh/> | Note: Usually a solitary lesion.<ref name=emedicine_fnh/> | ||
=== | ===Microscopic=== | ||
Features:<ref>{{Ref PBoD|922}}</ref> | Features:<ref>{{Ref PBoD|922}}</ref> | ||
*Stellate scar has large arteries with fibromuscular hyperplasia. | *Stellate scar has large arteries with fibromuscular hyperplasia. | ||
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***Normal hepatocytes between fibrous septae. | ***Normal hepatocytes between fibrous septae. | ||
DDx: | |||
*May be difficult to distinguish from hepatic adenoma if no scar and no ductal proliferation.<ref>STC. 19 Jan 2009.</ref> | *May be difficult to distinguish from hepatic adenoma if no scar and no ductal proliferation.<ref>STC. 19 Jan 2009.</ref> | ||
==Nodular regenerative hyperplasia== | ==Nodular regenerative hyperplasia== | ||