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Difference between revisions of "Liver pathology"
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→Steatosis of the liver
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**Histologically, these cells look like adipocytes. | **Histologically, these cells look like adipocytes. | ||
**Lipid-laden hepatocytes have gene activations suggestive of adipogenic-like transformation.<ref>URL: [http://www.jci.org/articles/view/20513/version/1 http://www.jci.org/articles/view/20513/version/1]. Accessed on: 23 September 2009.</ref> | **Lipid-laden hepatocytes have gene activations suggestive of adipogenic-like transformation.<ref>URL: [http://www.jci.org/articles/view/20513/version/1 http://www.jci.org/articles/view/20513/version/1]. Accessed on: 23 September 2009.</ref> | ||
*Donor livers with more fat = worse outcome.<ref name=pmid20644128>{{cite journal |author=Doyle MB, Vachharajani N, Wellen JR, ''et al.'' |title=Short- and long-term outcomes after steatotic liver transplantation |journal=Arch Surg |volume=145 |issue=7 |pages=653–60 |year=2010 |month=July |pmid=20644128 |doi=10.1001/archsurg.2010.119 |url=}}</ref> | |||
**One cut-point is 30% -- more than 30% and the liver is undesirable for transplantation.<ref>STC. 6 December 2010.</ref> | |||
====Microvesicular steatosis==== | ====Microvesicular steatosis==== | ||