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Difference between revisions of "Synovial chondromatosis"
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'''Synovial chondromatosis''' is a relative common pathology of the [[joint]]. It is also known as '''synovial osteochondromatosis'''. | |||
'''Loose body''' redirects to this page. | |||
==General== | |||
*Benign. | |||
**Malignant transformation rare <5%.<ref name=pmid17848703/> | |||
*Classically location: knee.<ref name=pmid17848703>{{Cite journal | last1 = Murphey | first1 = MD. | last2 = Vidal | first2 = JA. | last3 = Fanburg-Smith | first3 = JC. | last4 = Gajewski | first4 = DA. | title = Imaging of synovial chondromatosis with radiologic-pathologic correlation. | journal = Radiographics | volume = 27 | issue = 5 | pages = 1465-88 | month = | year = | doi = 10.1148/rg.275075116 | PMID = 17848703 | URL = http://radiographics.rsna.org/content/27/5/1465.long }}</ref> | |||
**Hip next most common site. | |||
*Usually adults. | |||
*Prevalence: male > female. | |||
Note: | |||
*This is a clinicoradiologic diagnosis. | |||
==Gross/radiology== | |||
*Intraarticular calcifications. | |||
*Diffuse involvement of the joint. | |||
*+/-Loose bodies in the joint ([[AKA]] ''joint mice''). | |||
Image: | |||
*[http://commons.wikimedia.org/wiki/File:ChondromatoseCoude.jpg Synovial chondromatosis (WC)]. | |||
*[http://radiographics.rsna.org/content/27/5/1465/F26.expansion.html SC - gross (rsna.org)]. | |||
==Microscopic== | |||
Features:<ref name=pmid17848703/> | |||
*[[Hyaline cartilage]] +/- lobular surface. | |||
**+/-Lacunae with binucleate cells. | |||
**+/-Nuclear atypia - moderate to severe.<ref>URL: [http://www.webpathology.com/image.asp?n=3&Case=369 http://www.webpathology.com/image.asp?n=3&Case=369]. Accessed on: 10 December 2012.</ref> | |||
*+/-Synovial hyperplasia - ribbon like tissue with an epithelium that has eosinophilic cytoplasm. | |||
*[[Bone]]. | |||
DDx: | |||
*[[Chondrosarcoma]]. | |||
*[[Osteoarthritis]]. | |||
===Images=== | |||
www: | |||
*[http://radiographics.rsna.org/content/27/5/1465.long Synovial chondromatosis (rsna.org)]. | |||
*[http://radiographics.rsna.org/content/27/5/1465/F45.expansion.html Synovial chondromatosis - low mag. (rsna.org)]. | |||
*[http://www.webpathology.com/image.asp?n=1&Case=369 Synovial chondromatosis (webpathology.com)]. | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051128/figure/F0006/ Loose body with fibrotic synovial membrane (nih.gov)]. | |||
===Sign out=== | |||
<pre> | |||
LOOSE BODIES, RIGHT ELBOW, REMOVAL: | |||
- FRAGMENTS OF BONE WITH CARTILAGE AND SYNOVIAL TISSUE COMPATIBLE WITH LOOSE BODIES. | |||
</pre> | |||
<pre> | |||
TISSUE, CAPSULE LEFT ELBOW, REMOVAL: | |||
- DEGENERATIVE JOINT DISEASE. | |||
- SYNOVIAL HYPERPLASIA WITHOUT SIGNIFICANT INFLAMMATION. | |||
- ROUND BODIES CONSISTING OF BENIGN BONE WITH A FATTY MARROW, AND FIBROUS | |||
AND CARTILAGINOUS SURFACE, COMPATIBLE WITH LOOSE BODIES. | |||
- NEGATIVE FOR MALIGNANCY. | |||
</pre> | |||
<pre> | |||
LOOSE BODY, LEFT KNEE, REMOVAL: | |||
- BENIGN BONE WITH FIBROTIC SYNOVIAL MEMBRANE, CONSISTENT WITH LOOSE BODY. | |||
</pre> | |||
====Micro==== | |||
The sections show multiple fragments of tissue consisting of bone covered by hyaline cartilage and associated with synovial hyperplasia. | |||
There is no appreciable nuclear atypia or mitotic activity. | |||
==See also== | |||
*[[Cartilage]]. | |||
*[[Bone]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||