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Difference between revisions of "Exaggerated placental site"
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'''Exaggerated placental site''', abbreviated '''EPS''', is an uncommon benign pathology that is a | |||
[[gestational trophoblastic disease]]. | |||
It was previously known as '''syncytial endometritis'''.<ref>URL: [http://www.webpathology.com/image.asp?case=565&n=7 http://www.webpathology.com/image.asp?case=565&n=7]. Accessed on: 22 May 2014.</ref> | |||
==General== | |||
*Benign. | |||
Definition: | |||
*"Increased number" of implantation-site [[Intermediate trophoblast|intermediate trophoblastic cells]]. | |||
Note: | |||
*Used to go by a terrible old term: ''syncytial endometritis'':<ref name=ouhsc_kfung>URL: [http://moon.ouhsc.edu/kfung/IACP-OLP/TC-Text/TC-01-Supp.pdf http://moon.ouhsc.edu/kfung/IACP-OLP/TC-Text/TC-01-Supp.pdf]. Accessed on: 15 August 2011.</ref> | |||
**Not syncytial -- mostly. | |||
**Not inflammatory. | |||
==Microscopic== | |||
Features:<ref name=ouhsc_kfung/> | |||
*Intermediate trophoblast: | |||
**Abundant (eosinophilic) cytoplasm. | |||
*Usu. adjacent to: | |||
**[[Chorionic villi]]. | |||
**Decidua - endometrial stromal cells with a nucleus central, eosinphilic cytoplasm, well-defined cell borders. | |||
*No mitotic activity. | |||
*Ectatic blood vessels. | |||
DDx: | |||
*[[PSTT]]. | |||
==IHC== | |||
*MIB1 ~0%. | |||
**Used to differentiate from [[PSTT]]. | |||
==See also== | |||
*[[Gestational trophoblastic disease]]. | |||
*[[Endometritis]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Gestational trophoblastic disease]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||