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Difference between revisions of "Basics"
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→Lung granulomata: +fibrin-ring
m (→Necrosis) |
(→Lung granulomata: +fibrin-ring) |
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| Line 308: | Line 308: | ||
*Churg-Strauss disease, | *Churg-Strauss disease, | ||
*Rheumatoid nodules. | *Rheumatoid nodules. | ||
===Special granulomas=== | |||
Fibrin ring granuloma. | |||
*Classically associated with ''Q fever''. | |||
**DDx:<ref name=pmid11881318>{{cite journal |author=Tjwa M, De Hertogh G, Neuville B, Roskams T, Nevens F, Van Steenbergen W |title=Hepatic fibrin-ring granulomas in granulomatous hepatitis: report of four cases and review of the literature |journal=Acta Clin Belg |volume=56 |issue=6 |pages=341–8 |year=2001 |pmid=11881318 |doi= |url=}}</ref> infections (Coxiella burneti (causes Q fever), CMV, EBV + others), drug reaction, malignancy (e.g. Hodgkin lymphoma<ref name=pmid8514044>{{cite journal |author=de Bayser L, Roblot P, Ramassamy A, Silvain C, Levillain P, Becq-Giraudon B |title=Hepatic fibrin-ring granulomas in giant cell arteritis |journal=Gastroenterology |volume=105 |issue=1 |pages=272–3 |year=1993 |month=July |pmid=8514044 |doi= |url=}}</ref>). | |||
*Appearance: | |||
**Epithelioid macrophages (i.e. a granuloma) surrounding a fibrin ring with a clear (lipid-filled) vacuole at its center. | |||
==Common morphologic problems== | ==Common morphologic problems== | ||