Difference between revisions of "Immune thrombocytopenic purpura"

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==General==
==General==
Presentation:
*Bleeding - usually.<ref name=pmid23714309>{{cite journal |author=Kistangari G, McCrae KR |title=Immune thrombocytopenia |journal=Hematol. Oncol. Clin. North Am. |volume=27 |issue=3 |pages=495–520 |year=2013 |month=June |pmid=23714309 |doi=10.1016/j.hoc.2013.03.001 |url=}}</ref>
Treatment:
*Usually treated with corticosteroids.<ref name=pmid23714309/>
**Possibly retuximab.<ref>{{Cite journal  | last1 = Zhang | first1 = C. | last2 = Liu | first2 = HF. | last3 = Chen | first3 = XH. | last4 = Gao | first4 = L. | last5 = Gao | first5 = L. | last6 = Liu | first6 = Y. | last7 = Kong | first7 = PY. | last8 = Sun | first8 = AH. | last9 = Zhang | first9 = X. | title = Is splenectomy necessary for immune thrombocytopenic purpura? The role of rituximab in patients with corticosteroid resistance in a single-center experience. | journal = Clin Ther | volume = 36 | issue = 3 | pages = 385-8 | month = Mar | year = 2014 | doi = 10.1016/j.clinthera.2014.01.017 | PMID = 24594069 }}</ref>
*Refractory cases get a splenectomy.
Prevalence:
*Uncommon.
*Uncommon.
*Usually treated with corticosteroids and splenectomy.<ref>{{Cite journal  | last1 = Zhang | first1 = C. | last2 = Liu | first2 = HF. | last3 = Chen | first3 = XH. | last4 = Gao | first4 = L. | last5 = Gao | first5 = L. | last6 = Liu | first6 = Y. | last7 = Kong | first7 = PY. | last8 = Sun | first8 = AH. | last9 = Zhang | first9 = X. | title = Is splenectomy necessary for immune thrombocytopenic purpura? The role of rituximab in patients with corticosteroid resistance in a single-center experience. | journal = Clin Ther | volume = 36 | issue = 3 | pages = 385-8 | month = Mar | year = 2014 | doi = 10.1016/j.clinthera.2014.01.017 | PMID = 24594069 }}</ref>
 
===Classification===
*Primary.
*Secondary.
**Viral.
**Bacterial - possibly [[Helicobacter pylori]].<ref>{{cite journal |author=Kuwana M |title=Helicobacter pylori-associated immune thrombocytopenia: clinical features and pathogenic mechanisms |journal=World J. Gastroenterol. |volume=20 |issue=3 |pages=714–23 |year=2014 |month=January |pmid=24574745 |pmc=3921481 |doi=10.3748/wjg.v20.i3.714 |url=}}</ref>


==Gross==
==Gross==
48,830

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