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Difference between revisions of "Endocervical adenocarcinoma in situ"
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Endocervical adenocarcinoma in situ (view source)
Revision as of 17:55, 2 May 2014
, 17:55, 2 May 2014→IHC: +SO
(→IHC: +SO) |
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| Line 88: | Line 88: | ||
*CEA +ve. | *CEA +ve. | ||
*Vimentin -ve. | *Vimentin -ve. | ||
==Sign out== | |||
<pre> | |||
UTERINE CERVIX, BIOPSY: | |||
- HIGH-GRADE SQUAMOUS INTRAEPITHELIAL LESION (HSIL). | |||
- ENDOCERVICAL ADENOCARCINOMA IN SITU (AIS). | |||
- ACUTE AND CHRONIC INFLAMMATION. | |||
COMMENT: | |||
A p16 immunostain marks the full thickness of the squamous epithelium and is | |||
strong. A Ki-67 immunostain marks increased numbers of superficial squamous cells. | |||
The atypical endocervical epithelium (interpreted as AIS) is strongly p16 positive | |||
and has an increased proliferative activity with Ki-67 staining. | |||
</pre> | |||
===Micro=== | |||
The atypical endocervical epithelium (interpreted as AIS) shows marked hyperchromasia, nuclear crowding and moderate nuclear atypia with a relatively abundant cytoplasm ( nucleus to cell size = 1:2 ). | |||
==See also== | ==See also== | ||