48,847
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Difference between revisions of "Neuropathology tumours"
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m
→Chordoma
m (→Microscopic: wikify) |
m (→Chordoma) |
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*#*Have a very large clear bubble with a sharp border; bubble does not compress nucleus - nucleus may be in bubble. | *#*Have a very large clear bubble with a sharp border; bubble does not compress nucleus - nucleus may be in bubble. | ||
Images: | |||
*[http://library.med.utah.edu/WebPath/COW/COW062.html Chordoma (med.utah.edu)]. | |||
*[http://www.ucl.ac.uk/cancer/research-groups/genetics-of-sarcoma/index.htm Chordoma - several images (acl.ac.uk)]. | |||
*[http://www.surgical-pathology.com/Chordoma4_image.htm Chordoma - crappy quality image (surgical-pathology.com)]. | *[http://www.surgical-pathology.com/Chordoma4_image.htm Chordoma - crappy quality image (surgical-pathology.com)]. | ||
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*S100 +ve. | *S100 +ve. | ||
*CK +ve. | *CK +ve. | ||
*Brachyury +ve. | *Brachyury +ve -- '''key stain'''. | ||
**Protein important for axial development, affects notochord development.<ref>URL:[http://www.ncbi.nlm.nih.gov/omim/601397 http://www.ncbi.nlm.nih.gov/omim/601397]. Accessed on: 18 May 2010.</ref> | **Protein important for axial development, affects notochord development.<ref>URL:[http://www.ncbi.nlm.nih.gov/omim/601397 http://www.ncbi.nlm.nih.gov/omim/601397]. Accessed on: 18 May 2010.</ref> | ||
**''Brachyury'' literally means ''short tail''.<ref>URL: [http://www.jstor.org/pss/86845 http://www.jstor.org/pss/86845]. Accessed on: 18 May 2010.</ref> | **''Brachyury'' literally means ''short tail''.<ref>URL: [http://www.jstor.org/pss/86845 http://www.jstor.org/pss/86845]. Accessed on: 18 May 2010.</ref> | ||