Difference between revisions of "Prostate gland"

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Prostate gland (view source)

Revision as of 01:49, 29 April 2014

1,540 bytes removed ,  01:49, 29 April 2014
→‎Atrophy of the prostate: split out
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*[[AKA]] ''prostatic atrophy''.
*[[AKA]] ''prostatic atrophy''.
*[[AKA]] ''atrophy of the prostate gland''.
*[[AKA]] ''atrophy of the prostate gland''.
===General===
{{Main|Atrophy of the prostate gland}}
*Small glands (may mimic Gleason score 3 pattern).
 
===Microscopic===
Features:
*Glands often have a jagged edges/prows (in cancer the glands tend to have round edges) - '''key feature'''.
**Prow = forward most part of a ship's bow that cuts through the water.<ref>[http://en.wikipedia.org/wiki/Prow http://en.wikipedia.org/wiki/Prow]</ref>
***You may have come across ''prow'' in the context of [[breast cancer]], i.e. ''tubular carcinoma''.
*Gland density is usually lower than in prostate carcinoma, i.e. glands are not back-to-back - '''key feature'''.
*Atrophic glands are often hyperchromatic.<ref>SN. June 3, 2009.</ref>
*Scant cytoplasm - usually.
 
Negatives:
*Nuclei like normal, i.e. nucleoli uncommon.
*Should have two cell layers, i.e. epithelial and myoepithelial (may be difficult to see).
 
Notes:
*Atrophic glands may be scattered with non-atrophic ones.
*IHC may be misleading - basal cell loss.
 
DDx:
*[[Atrophic prostate carcinoma]].
 
====Atrophy versus cancer====
{| class="wikitable sortable"
! Histologic feature
! Atrophy
! Cancer
|-
|Glandular architecture/<br>arrangement
|angulated glands, may <br>look like they originate <br>from one large duct
|round glands, <br>often back-to-back
|-
|Nuclear <br>hyperchromasia
|marked
|moderate
|-
|Cytoplasm
|scant/minimal
|moderate, may <br>be amphophilic
|-
|Basal cells
|may be visible
|absent
|-
|Nucleoli
|absent
|present
|-
|Secretions in <br>glands
|no
|yes - eosinophilic <br>or blue
|}
 
===Sign out===
Generally, this finding is ''not'' reported; it is considered a normal finding.


==Prostatic infarct==
==Prostatic infarct==
Michael
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