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<pre> | |||
SKIN LESION, BACK, PUNCH BIOPSY: | |||
- BENIGN INTRADERMAL NEVUS. | |||
</pre> | |||
====Adipocytes present==== | |||
<pre> | |||
SKIN LESION, BACK, PUNCH BIOPSY: | |||
- BENIGN INTRADERMAL NEVUS WITH MATURE ADIPOCYTES. | |||
</pre> | |||
====Clinically suspicious==== | |||
<pre> | |||
SKIN LESION, LEFT UPPER ARM, PUNCH BIOPSY: | |||
- BENIGN INTRADERMAL NEVUS, INCOMPLETELY EXCISED. | |||
COMMENT: | |||
HMB-45 marks very rare superficial cells. Ki-67 staining does not show apparent melanocyte | |||
staining. MITF marks the melanocytes and demonstrates maturation of the melanocytes with depth. | |||
</pre> | |||
===Micro=== | |||
The sections show melanocytes in the dermis separated from the epidermis by a Grenz zone. The lesion is symmetrical in its architecture and pigment distribution. Superficially, melanocytes are in nests. Melanocytes mature with depth. No mitotic activity is appreciated. | |||
The lesion is completely excised in the plane of section. | |||
====IDN with congenital features==== | |||
The sections show melanocytes in the dermis separated from the epidermis by a Grenz | |||
zone. The lesion is symmetrical in its architecture. Superficially, melanocytes are in | |||
nests. Melanocytes mature with depth and track along adnexal structures. No mitotic | |||
activity is appreciated. The lesion is incompletely excised in the plane of section. | |||
==See also== | ==See also== |
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