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| ====Intradermal melanocytic nevus==== | | ====Intradermal melanocytic nevus==== |
| <pre>
| | {{Main|Intradermal nevus}} |
| SKIN LESION, BACK, PUNCH BIOPSY:
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| - BENIGN INTRADERMAL NEVUS.
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| </pre>
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| =====Adipocytes present=====
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| <pre>
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| SKIN LESION, BACK, PUNCH BIOPSY:
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| - BENIGN INTRADERMAL NEVUS WITH MATURE ADIPOCYTES.
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| </pre>
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| | |
| =====Clinically suspicious=====
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| <pre>
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| SKIN LESION, LEFT UPPER ARM, PUNCH BIOPSY:
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| - BENIGN INTRADERMAL NEVUS, INCOMPLETELY EXCISED.
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| COMMENT:
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| HMB-45 marks very rare superficial cells. Ki-67 staining does not show apparent melanocyte
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| staining. MITF marks the melanocytes and demonstrates maturation of the melanocytes with depth.
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| </pre>
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| =====Micro=====
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| The sections show melanocytes in the dermis separated from the epidermis by a Grenz zone. The lesion is symmetrical in its architecture and pigment distribution. Superficially, melanocytes are in nests. Melanocytes mature with depth. No mitotic activity is appreciated.
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| The lesion is completely excised in the plane of section.
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| ======IDN with congenital features======
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| The sections show melanocytes in the dermis separated from the epidermis by a Grenz
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| zone. The lesion is symmetrical in its architecture. Superficially, melanocytes are in
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| nests. Melanocytes mature with depth and track along adnexal structures. No mitotic
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| activity is appreciated. The lesion is incompletely excised in the plane of section.
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| ==Congenital-pattern nevus== | | ==Congenital-pattern nevus== |