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==Craniopharyngioma== | ==Craniopharyngioma== | ||
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* | ===General=== | ||
*Develop from remains of Rathke's pouch or squamous epithelial cell rests.<ref name=pmid17425791>{{Cite journal | last1 = Garnett | first1 = MR. | last2 = Puget | first2 = S. | last3 = Grill | first3 = J. | last4 = Sainte-Rose | first4 = C. | title = Craniopharyngioma. | journal = Orphanet J Rare Dis | volume = 2 | issue = | pages = 18 | month = | year = 2007 | doi = 10.1186/1750-1172-2-18 | PMID = 17425791 }}</ref> | |||
Comes in two flavours:<ref name=pmid17425791/> | |||
*Adamantinomatous type. | |||
*Squamous papillary type. | |||
Radiology:<ref name=pmid17425791/> | |||
*Calcified (adamantinomatous type). | |||
*Solid & cystic. | |||
===Microscopic=== | |||
Features (adamantinomatous):<ref name=Ref_DCHH184>{{Ref DCHH|184}}</ref> | |||
*Well-circumscribed (or pseudoinvasive border). | |||
*Multicystic. | |||
*Small-to-medium sized cells with moderate amount of basophilic cytoplasm. | |||
*Bland nuclei (with occ. small nucleoli). | |||
*"Wet" keratin - nests of whorled keratin. | |||
*Calcifications (non-psammomatous). | |||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Adamantinomatous_craniopharyngioma_-_very_low_mag.jpg Adamantinomatous craniopharyngioma - very low mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Adamantinomatous_craniopharyngioma_-_intermed_mag.jpg Adamantinomatous craniopharyngioma - intermed. mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Adamantinomatous_craniopharyngioma_-_very_high_mag.jpg Adamantinomatous craniopharyngioma - very high mag. (WC)]. | |||
==Necrosis== | ==Necrosis== |
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