Difference between revisions of "An introduction to head and neck pathology"

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An introduction to head and neck pathology (view source)

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==Craniopharyngioma==
==Craniopharyngioma==
===General===
{{Main|Craniopharyngioma}}
*Develop from remains of Rathke's pouch or squamous epithelial cell rests.<ref name=pmid17425791>{{Cite journal  | last1 = Garnett | first1 = MR. | last2 = Puget | first2 = S. | last3 = Grill | first3 = J. | last4 = Sainte-Rose | first4 = C. | title = Craniopharyngioma. | journal = Orphanet J Rare Dis | volume = 2 | issue =  | pages = 18 | month =  | year = 2007 | doi = 10.1186/1750-1172-2-18 | PMID = 17425791 }}</ref>
*Cystic lesion +/- calcifications +/-squamous nests.
 
*Related to ''Rathke cleft cyst''.
Comes in several flavours:<ref name=pmid17425791/>
*Adamantinomatous type. 
*Squamous papillary type.
 
Radiology:<ref name=pmid17425791/>
*Calcified.
*Solid & cystic.
 
===Microscopic===
Features (adamantinomatous):<ref name=Ref_DCHH184>{{Ref DCHH|184}}</ref>
*Well-circumscribed (or pseudoinvasive border).
*Multicystic.
*Small-to-medium sized cells with moderate amount of basophilic cytoplasm.
*Bland nuclei (with occ. small nucleoli).
*"Wet" keratin - nests of whorled keratin.
*Calcifications (non-psammomatous).
 
Images:
*[http://commons.wikimedia.org/wiki/File:Adamantinomatous_craniopharyngioma_-_very_low_mag.jpg Adamantinomatous craniopharyngioma - very low mag. (WC)].
*[http://commons.wikimedia.org/wiki/File:Adamantinomatous_craniopharyngioma_-_intermed_mag.jpg Adamantinomatous craniopharyngioma - intermed. mag. (WC)].
*[http://commons.wikimedia.org/wiki/File:Adamantinomatous_craniopharyngioma_-_very_high_mag.jpg Adamantinomatous craniopharyngioma - very high mag. (WC)].


==Nasopharyngeal angiofibroma==
==Nasopharyngeal angiofibroma==
Michael
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