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| =Adipocytic tumours= | | =Adipocytic tumours= |
| ==Hibernoma==
| | {{Main|Adipocytic tumours}} |
| ===General===
| |
| *Consists of ''brown fat'' (present in the infants to generate heat).<ref name=Ref_WMSP605>{{Ref WMSP|605}}</ref>
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| *Benign.
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| *Usually asymptomatic.<ref name=pmid19131775>{{cite journal |author=Ahmed SA, Schuller I |title=Pediatric hibernoma: a case review |journal=J. Pediatr. Hematol. Oncol. |volume=30 |issue=12 |pages=900–1 |year=2008 |month=December |pmid=19131775 |doi=10.1097/MPH.0b013e318184e6dd |url=}}</ref>
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| ===Epidemiology===
| | This category includes: |
| *Young adults.
| | *Lipoma. |
| | | *Liposarcoma. |
| ===Gross===
| | *Hibernoma. |
| *Well-circumscribed.
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| *Lobulated and light-brown on sectioning.
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| | |
| ===Microscopic===
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| Features:<ref>{{cite journal |author=Chen DY, Wang CM, Chan HL |title=Hibernoma. Case report and literature review |journal=Dermatol Surg |volume=24 |issue=3 |pages=393–5 |year=1998 |month=March |pmid=9537018 |doi= |url=}}</ref>
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| *Large polygonal/oval cells: | |
| **Nucleus - central & small.<ref>[http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675(06)70271-6 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675(06)70271-6]</ref>
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| ***Nucleoli typically prominent.<ref>[http://surgpathcriteria.stanford.edu/softfat/hibernoma/ http://surgpathcriteria.stanford.edu/softfat/hibernoma/]</ref> | |
| **Cytoplasm - multivacuolated, oval, eosinophilic, granular. | |
| | |
| Image:
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| *[http://en.wikipedia.org/wiki/File:Hibernoma1.jpg Hibernoma (WC)].
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| ==Liposarcoma==
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| *Most common malignant sarcoma in the retroperitoneum.
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| ===Microscopy===
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| Features:
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| *Lipoblasts:
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| **Large sharply demarcated vacuole.
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| **Nucleus:
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| ***Hyperchromatic (dark staining) nucleus.
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| ***Eccentric location.
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| ***Nuclear indentation.
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| Images:
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| *[http://commons.wikimedia.org/wiki/File:Myxoid_liposarcoma_%2806%29.JPG Myxoid liposarcoma (WC)].
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| *[http://commons.wikimedia.org/wiki/File:Myxoid_liposarcoma_%2805%29.JPG Myxoid liposarcoma (WC)].
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| *[http://www.john-libbey-eurotext.fr/e-docs/00/04/09/14/texte_alt_jleejd00046_gr5.jpg Lipoblasts (john-libbey-eurotext.fr)].
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| | |
| ===IHC===
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| *IHC is of limited value.
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| *S-100 +ve ~1/3 of the time.
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| *Reticulin ???.
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| =Smooth muscle tumours= | | =Smooth muscle tumours= |