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| ==Aneurysmal bone cyst== | | ==Aneurysmal bone cyst== |
| *Abbreviated ''ABC''.
| | {{Main|Aneurysmal bone cyst}} |
| :''Also see [[giant cell reparative granuloma]]'' ([[AKA]] ''solid aneurysmal bone cyst'').
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| ===General===
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| Features:<ref name=emed_abc>URL: [http://emedicine.medscape.com/article/1254784-overview http://emedicine.medscape.com/article/1254784-overview]. Accessed on: 4 February 2011.</ref>
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| *Benign.
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| **May grow rapidly.
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| *Osteolysis -> cystic space -> filled with blood.
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| *Relatively common; in children second only to [[osteosarcoma]].<ref name=pmid18157043>{{cite journal |author=van den Berg H, Kroon HM, Slaar A, Hogendoorn P |title=Incidence of biopsy-proven bone tumors in children: a report based on the Dutch pathology registration "PALGA" |journal=J Pediatr Orthop |volume=28 |issue=1 |pages=29–35 |year=2008 |pmid=18157043 |doi=10.1097/BPO.0b013e3181558cb5 |url=}}</ref>
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| ===Gross/radiologic===
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| Features:<ref name=pmid22531523>{{Cite journal | last1 = Parashari | first1 = UC. | last2 = Khanduri | first2 = S. | last3 = Upadhyay | first3 = D. | last4 = Bhadury | first4 = S. | last5 = Singhal | first5 = S. | title = Radiologic and pathologic correlation of aneurysmal bone cysts at unusual sites. | journal = J Cancer Res Ther | volume = 8 | issue = 1 | pages = 103-5 | month = | year = | doi = 10.4103/0973-1482.95183 | PMID = 22531523 }}</ref>
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| *Air-fluid levels (radiology).
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| *Usually metaphysis of long bones, but uncommonly the femur.
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| *May have an "aggressive" appearance, i.e. erode bone.
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| ===Microscopic===
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| Features:<ref name=emed_abc/>
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| *Bony trabeculae ''or'' osteoid tissue.
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| *Osteoclast [[giant cell]]s.
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| **Multi-nucleated giant-cells with round randomly arranged nuclei.
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| *Benign spindle cells (fibroblasts) - surround bone/adjacent to the giant cells - '''important'''.
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| *Blood +/- surrounded by giant cells.
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| DDx:
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| *[[Giant cell tumour of bone]] - the nuclei of the cells surrounding the giant cells are similar to those in the giant cells (round nuclei).
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| *[[Telangiectatic osteosarcoma]].
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| *Other [[giant cell lesions]].
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| ====Images====
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| <gallery>
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| Image:Aneurysmal_bone_cyst_-_intermed_mag.jpg | ABC - intermed. mag. (WC/Nephron)
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| Image:Aneurysmal_bone_cyst_-_very_high_mag.jpg | ABC - very high mag. (WC/Nephron)
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| </gallery>
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| www:
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| *[http://www.webpathology.com/image.asp?n=4&Case=344 ABC - low mag. (webpathology.com)].
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| *[http://www.webpathology.com/image.asp?n=5&Case=344 ABC - intermed. mag. (webpathology.com)].
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| *[http://www.webpathology.com/image.asp?case=344&n=6 ABC - high mag. (webpathology.com)].
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| ==Myositis ossificans== | | ==Myositis ossificans== |