Difference between revisions of "Pulmonary pathology"

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Pulmonary pathology (view source)

Revision as of 18:36, 3 March 2014

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→‎Pulmonary hamartoma: split out
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==Pulmonary hamartoma==
==Pulmonary hamartoma==
===General===
{{Main|Pulmonary hamartoma}}
*Benign.
 
See also: ''[[Hamartoma]]''.
 
===Gross===
*Well circumscribed lesion.
 
===Microscopic===
Features:
*Cartilage - '''key feature'''.
**Single cells in lacunae surrounded by abundant matrix.
***Paucicellular vis-a-vis malignant lesions.
*Fat (adipocytes) - '''key feature'''.
*Respiratory epithelium (columnar epithelium with cilia).
 
Notes:
*No nuclear atypia.
 
====Images====
www:
*[http://forums.studentdoctor.net/showthread.php?t=207741 Pulmonary hamartoma (studentdoctor.net)].
*[http://www.path.utah.edu/casepath/pm%20cases/pmcase8/Hamartoma2.jpg Lung hamartoma (path.utah.edu)].<ref>URL: [http://www.path.utah.edu/casepath/pm%20cases/pmcase8/pmcase8part4.htm http://www.path.utah.edu/casepath/pm%20cases/pmcase8/pmcase8part4.htm]. Accessed on: 9 June 2011.</ref>
<gallery>
Image:Pulmonary_hamartoma_-_low_mag.jpg | Pulmonary hamartoma - low mag. (WC)
Image:Pulmonary_hamartoma_-_intermed_mag.jpg | Pulmonary hamartoma - intermed. mag. (WC)
Image:Pulmonary_hamartoma_-_high_mag.jpg | Pulmonary hamartoma - high mag. (WC)
</gallery>
 
===IHC===
*S100 +ve - highlights the fat.
 
===Sign out===
<pre>
LUNG LESION, LEFT UPPER LOBE, WEDGE RESECTION:
- PULMONARY HAMARTOMA WITH MILD FOCAL ACUTE INFLAMMATION AND SURROUNDING EDEMA.
- SURROUNDING LUNG WITH MILD EMPHYSEMATOUS CHANGES.
</pre>
 
====Micro====
The sections show lung with a well circumscribed lesion with a fibrous capsule partially lined by respiratory-type epithelium.  The lesion consists of abundant respiratory epithelium and glands with focal sheeting and small collections of neutrophils focally.  Small foci of degenerative changes are seen.  The epithelium of the lesion as a gland cytomorphology.  Mitotic activity is not readily apparent.  Fat is not identified as a component of the lesion.  Around the periphery of the lesion pulmonary edema is present. 
 
The piece surrounding lung more distant from the lesion has mild emphysematous changes.  No interstitial fibrosis is identified.  No significant inflammation is present.  The arteries are approximately the size of accompanying airway.  The arteries have no appreciable intimal thickening.


==Malformations==
==Malformations==
Michael
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